Cefixime 头孢克肟
CAS 79350-37-1 MFCD00865020
化学结构图
SMILES: C=CC1CS[C@@H]2[C@H](NC(=O)/C(=N\OCC(O)=O)/C3=CSC(N)=N3)C(=O)N2C=1C(O)=O
化学属性
| Mol. Formula | C16H15N5O7S2 |
|---|---|
| Mol. Weight | 453 |
| Density | |
| Boiling Point | |
| Melting Point |
别名和识别编码
| Chemical Name | Cefixime |
|---|---|
| CAS Number | 79350-37-1 |
| Synonym | (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid CL 284635 CL-284635 Cefixime Cefixoral Cefspan FK 027 FK-027 FR 17027 FR- 17027 |
| Chemical Name Translation | 头孢克肟 |
| Beilstein Registry Number | 6025058 |
| EC Number | |
| MDL Number | MFCD00865020 |
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信息真实价格透明
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现货库存
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分类
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds,
产品应用
- Orally active, third generation cephalosporin antibiotic.
相关文献及参考
- Kamimura, T., et al.: Antimicrob. Agents Chemother., 25, 98 (1984),
- Yamanaka, H., et al.: J. Antibiot., 38, 1738 (1985),
- Guay, D.R.P., et al.: Antimicrob. Agents Chemother., 30, 485 (1986),
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4420 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,19
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF T
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
GHS Symbol
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