Benz(a)anthracene, 7,12-dimethyl-5-fluoro-

CAS 794-00-3 MFCD00794003

化学结构图

794-00-3
SMILES: Cc1c2ccccc2c(C)c2c1cc(F)c1ccccc12

化学属性

Mol. FormulaC20H15F
Mol. Weight274.35

别名和识别编码

Chemical NameBenz(a)anthracene, 7,12-dimethyl-5-fluoro-
Chemicalbook IDCB12261060
Wiswesser Line NotationL D6 B666J C1 J1 MF
Synonym 7,12-Dimethyl-5-fluorobenz(a)anthracene 5-Fluoro-7,12-dimethylbenz(a)anthracene
CAS Number794-00-3
Beilstein Registry Number2563809
InChIKeyAXKHSIBLEVOWME-UHFFFAOYSA-N
PubChem Substance ID69927
InChIInChI=1S/C20H15F/c1-12-14-7-3-4-8-15(14)13(2)20-17-10-6-5-9-16(17)19(21)11-18(12)20/h3-11H,1-2H3
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 823 mg/kg/10W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,1076,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 110 ug/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,411,1979

RTECSCW4410000
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 70 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 92,427,1982

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 38 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   39,411,1979

系列性分类


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