Saponin 皂素

CAS 8047-15-2 MFCD00081981

化学结构图

8047-15-2
SMILES: C/C=C(\C)C(=O)OC1C(OC(C)=O)C2(CO)C(O)CC3(C)C(=CCC4C5(C)CCC(OC6OC(C(=O)O)C(OC7OC(CO)C(O)C(O)C7O)C(O)C6OC6OC(CO)C(O)C(O)C6O)C(C)(CO)C5CCC43C)C2CC1(C)C

化学属性

Mol. FormulaN/A
Melting Point158° dec.
TSCAYes
Mol. Weight1
Density1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)
Stability易吸潮

别名和识别编码

MDL NumberMFCD00081981
CAS Number8047-15-2
EC Number232-462-6
PubChem Substance ID6540709
Merck Number14,8365
Synonym 茶皂素 Saponin 来源于皂树皮 皂素 皂苷;肥皂草素;皂草苷;皂角苷;茶皂素;地奥配基;皂甙 皂素/茶皂素 地奥配基 薯芋皂苷元 Sapogenins glycosides 皂甙 皂苷,肥皂草素,皂草苷,皂角苷
Chemical NameSaponin
Chemical Name Translation皂素
InChIInChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10-/t26?,27-,28-,29?,30?,31-,32+,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43+,44+,47+,48+,49-,51+,52-,53-,54-,55+/m1/s1
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分类

  • {SA} Antigen-Vaccine Preparation, Cell Biology, Cell Culture, Cell Lysis Reagents, Cell Signaling and Neuroscience, Core Bioreagents, Detergents, Detergents N to Z,
  • {SNA} Antigen-Vaccine Preparation,
  • Antigen-Vaccine Preparation, Cell Biology, Cell Culture, Cell Lysis Reagents, Cell Signaling and Neuroscience, Detergents, Detergents N to Z, Detergents by Applications, Diagnostic Applications, Drug Delivery-Liposomes, Molecular Biology, Non-Ionic Detergents, Other adjuvants, Signal Transduction Research Tools, Vaccine Adjuvants, Vaccine Production
  • {SNA} Antigen-Vaccine Preparation,

产品应用

  • 临床化验中用于血液氧容量和氧含量测定。以火焰原子吸收光度测定牛乳中金属用洗涤剂。电子计数白细胞周围血液中找肿瘤细胞。乳化剂。发泡剂。防腐剂。

相关文献及参考

  • Spillman, N.J., et al., Acid extrusion from the intraerythrocytic malaria parasite is not via a Na(+)/H(+) exchanger. Mol. Biochem. Parasitol. 162 , 96-9, (2008) 摘要
  • Park, J.Y., et al., Microbubble suspension as a carrier of oxygen and acclimated bacteria for phenanthrene biodegradation. J. Hazard. Mater. 163 , 761-7, (2009) 摘要
  • Potter, W.B., et al., Metabolic Regulation Of Neuronal Plasticity By The Energy Sensor AMPK. PLoS Biol. 5 , e8996, (2010)
  • Cainelli, G., et al. Biotechnol. Appl. Biochem. 22 , 31, (1995) 摘要
  • Jalal, F., et al. Biochem. J. 288 , 945, (1992) 摘要
  • Hedman, K. J. Histochem. Cytochem. 28 , 1233, (1980)
  • Dourmashkin, R.R., et al. Nature 194 , 1116, (1962) 摘要

安全信息

Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
RTECSVQ1400000
GHS Symbol
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
WGK Germany2
Signal word Warning
Hazard statements
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护；
Risk Statements
  • R36/37 Irritating to eyes and respiratory system 对眼睛和呼吸系统有刺激性
Storage condition 密封干燥保存。 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1395,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1395,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1395,1935

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1394,19

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 350 mg/kg
SEX/DURATION            : female 9-22 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   TRBMAV Texas Reports on Biology and Medicine.  (Galveston, TX)  V.1-41(2),
   1943-81/82.  Discontinued.  Volume(issue)/page/year: 30,319,1972

其他信息

  • 一种从植物中提取的结构复杂的糖苷。有辛苦焦味。味微甜后苦。有吸湿性。溶于水和热水中溶解度可因加入少量碱而降低。

系列性分类

  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Anionic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Non-Ionic Detergents - Detergents
  1. Application Areas 应用领域分类
  2. Detergents 去污剂洗净剂
  3. Non-Ionic Detergents - Detergents
  1. Research Essentials 基础科研
  2. Core Bioreagents - Research Essentials
  3. Life Science Reagents for Immunohistochemistry (IHC) - Core Bioreagents
  4. Tissue Processing - Life Science Reagents for Immunohistochemistry (IHC)
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Signal Transduction Research Tools - Cell Signaling and Neuroscience
  5. Cell Lysis Reagents - Signal Transduction Research Tools
  6. Detergents - Cell Lysis Reagents

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