Propanoic acid,2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino )-2-oxoethylidine)amino)oxy)-2-methyl-,(2S-(2-alpha,3-beta(Z)))-, disodium salt

CAS 80581-86-8 MFCD01697529

化学结构图

80581-86-8
SMILES: [Na+].[Na+].C[C@H]1C(NC(=O)/C(=N\OC(C)(C)C([O-])=O)/C2=CSC(N)=N2)C(=O)N1S([O-])(=O)=O

化学属性

Mol. FormulaC13H15N5O8S2.2Na
Mol. Weight479.43

别名和识别编码

Chemical NamePropanoic acid,2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino )-2-oxoethylidine)amino)oxy)-2-methyl-,(2S-(2-alpha,3-beta(Z)))-, disodium salt
Synonym Azactam disodium Azthreonam disodium Aztreonam disodium
CAS Number80581-86-8
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安全信息

RTECSUA2451500 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACHDX Journal of Antimicrobial Chemotherapy.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1975-  Volume(issue)/page/year:
   8(Suppl E),141,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JACHDX Journal of Antimicrobial Chemotherapy.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1975-  Volume(issue)/page/year:
   8(Suppl E),141,1981

系列性分类

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