Trimeprazine 异丁嗪

CAS 84-96-8 MFCD00242597

化学结构图

84-96-8
SMILES: CC(CN(C)C)CN1c2ccccc2Sc2ccccc21

化学属性

Mol. FormulaC18H22N2S
Mol. Weight298.48
Melting Point68 ºC
Solubility0.942 MG/L

别名和识别编码

Chemical NameTrimeprazine
EC Number201-577-3
Synonym 10-[2-Methyl-3-(dimethylamino)propyl]phenothiazine 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl- 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl- ALIMENAZINE Alimemazine Alimemazine; N,N,2-Trimethyl-3-phenothiazin-10-yl-propan-1-amine Alimezine Bayer 1219 Isobutrazine Methylpromazine N,N,2-Trimethyl-3-(10H-phenothiazin-10-yl)-1-propanamine N,N,2-三甲基-3-吩噻嗪-10-基-1-丙胺 Nedeltran Panectyl Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]- Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]- (6CI, 8CI) Repeltin Spansule TRIMEPRAZINE Teralen Teralene Théralène Tr Trimeperazine
CAS Number84-96-8
Chemical Name Translation异丁嗪
Wiswesser Line NotationT C666 BN ISJ B1Y1&1N1&1
PubChem Substance ID5574
InChIInChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3
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安全信息

RTECSSO5700000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Behavioral - antipsychotic
REFERENCE :
   DNEUD5 Developments in Neuroscience (Amsterdam).  (Elsevier Science Pub.
   Co., Inc., 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 7,45,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANPBAZ Acta Neurologia et Psychiatrica Belgica.  (Brussels, Belgium)
   V.48-69, 1948-69.  For publisher information, see ANUBBR.
   Volume(issue)/page/year: 61,669,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANPBAZ Acta Neurologia et Psychiatrica Belgica.  (Brussels, Belgium)
   V.48-69, 1948-69.  For publisher information, see ANUBBR.
   Volume(issue)/page/year: 61,669,1961

Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P312
  • P301+P316
  • P301+P317
  • P302+P352
  • P305+P351+P338
  • P305+P354+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P317
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P333+P313
  • P333+P317
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • MOL 文件:84-96-8.mol
  • NIST化学物质信息:Trimeprazine(84-96-8)
  • 毒害物质数据:84-96-8(Hazardous Substances Data)

系列性分类


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