N-Carbamimidoyl-5-(5-Fluoro-2-Methylphenyl)Furan-2-Carboxamide N-氨基甲酰-5-(5-氟-2-甲基苯基)呋喃-2-甲酰胺

CAS 852146-73-7 MFCD08705324

化学结构图

852146-73-7
SMILES: CC1=CC=C(F)C=C1C1=CC=C(O1)C(=O)NC(N)=N

化学属性

Mol. FormulaC13H12FN3O2
Mol. Weight261.25

别名和识别编码

Chemical NameN-Carbamimidoyl-5-(5-Fluoro-2-Methylphenyl)Furan-2-Carboxamide
Synonym [5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine
MDL NumberMFCD08705324
PubChem Substance ID24724522
CAS Number852146-73-7
Chemical Name TranslationN-氨基甲酰-5-(5-氟-2-甲基苯基)呋喃-2-甲酰胺
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels, Ion Pump Inhibitors, K, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels
  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Ion Channels,
  • {SNA} Bioactive Small Molecule Alphabetical Index, Ion Channels, Ion Pump Inhibitors, K, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Roh, H.Y., et al., Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury. Pharmacology 75 , 37-44, (2005)

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
Hazard Codes Xn
WGK Germany3
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Ion Pump Inhibitors - Monovalent Ion Channels
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Sodium Channel Modulators - Monovalent Ion Channels
  8. Other Sodium Channel Modulators - Sodium Channel Modulators
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Ion Channels - Cell Signaling and Neuroscience
  5. Voltage-gated Ion Channels - Ion Channels
  6. Monovalent Ion Channels - Voltage-gated Ion Channels
  7. Sodium Channel Modulators - Monovalent Ion Channels
  8. Other Sodium Channel Modulators - Sodium Channel Modulators

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