N-Arachidonyl Maleimide
CAS 876305-42-9 MFCD11521506
化学结构图
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCN1C(=O)C=CC1=O
化学属性
| Mol. Formula | C24H35NO2 |
|---|---|
| Mol. Weight | 369.54 |
别名和识别编码
| Chemical Name | N-Arachidonylmaleimide |
|---|---|
| MDL Number | MFCD11521506 |
| CAS Number | 876305-42-9 |
| Synonym | |
| PubChem Substance ID | 329770807 |
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分类
- {SNA} AN-AZ, Bioactive Small Molecule Alphabetical Index, Cannabinoids, Metabolites, Inhibitors and Activators of Fatty Acid Metabolism, Monoacylglycerol Lipase Inhibitors, Neurobiology, Neuroscience, Pharmacologicals, 生物活性小分子, 癌症代谢, 癌症发生过程中的脂肪酸代谢, 癌症
相关文献及参考
- [2]. James J Burston, et al. N-arachidonyl Maleimide Potentiates the Pharmacological and Biochemical Effects of the Endocannabinoid 2-arachidonylglycerol Through Inhibition of Monoacylglycerol Lipase. J Pharmacol Exp Ther. 2008 Nov;327(2):546-53.
- Burston JJ, et al., N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase. Pharmacol. Ther. 327 , 546-553, (2008) 摘要
- Wang Y., et al., A fluorescence-based assay for monoacylglycerol lipase compatible with inhibitor screening. Drug Del. Tech. 6 , 387-393, (2008) 摘要
- Zvonok N., et al., Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis. Chem. Biol. 15 , 854-862, (2008)
- [1]. Susanna M Saario, et al. Characterization of the Sulfhydryl-Sensitive Site in the Enzyme Responsible for Hydrolys
安全信息
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
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