Enrofloxacin 恩氟沙星
CAS 93106-60-6 MFCD00792463
化学结构图
SMILES: CCN1CCN(CC1)C1=CC2=C(C=C1F)C(=O)C(=CN2C1CC1)C(O)=O
化学属性
| Mol. Formula | C19H22FN3O3 |
|---|---|
| Mol. Weight | 359.40 |
| TSCA | No |
| Melting Point | 222-228 |
别名和识别编码
| Chemical Name | Enrofloxacin |
|---|---|
| CAS Number | 93106-60-6 |
| Synonym | 1,4-Dihydro-1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-4-oxo-3-quinolinecarboxylic acid BAY VP 2674 Baytril 恩氟沙星 Enrofloxacin 1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo 恩诺沙星 |
| MDL Number | MFCD00792463 |
| PubChem Substance ID | 87560805 |
| Beilstein Registry Number | 5307824 |
| Merck Number | 3592 |
| Reaxys-RN | 5307824 |
| Chemical Name Translation | 恩氟沙星 |
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分类
- {SNA} A - K, Antibacterial, Antibiotics A to Z, Antibiotics A-F, Chemical Structure Class, Inhibits an Enzyme, Interferes with DNA Synthesis, Mechanism of Action, Quinolones and Fluoroquinolones, Spectrum of Activity, 抗生素, 生化试剂
- {SNA} 1694 Pharmaceuticals & Personal Care Products, A - K, APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F, Biochemicals and Reagents,
产品应用
- Fluorinated quinolone antibacterial.
相关文献及参考
- Altreuther, P., et al.: Vet. Med. Rev., 2, 87 (1987),
安全信息
- H303 May be harmfully swallowed 吞食可能有害
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
GHS Symbol
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4336 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VVMRDI VMR, Veterinary Medical Review. (N.G. Elwert Universitaets-und Verlagsbuchhandlung, Postfach 1128, 3550 Marburg, Fed. Rep. Ger.) No.1- 1976- Volume(issue)/page/year: 2,87,1987
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 60 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 248,135,1991
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