2,4-Dichlorophenoxyacetic acid 2,4-二氯苯氧乙酸

CAS 94-75-7 MFCD00004300

化学结构图

94-75-7
SMILES: O=C(O)COc1ccc(Cl)cc1Cl

化学属性

Mol. FormulaCl2C6H3OCH2CO2H
Mol. Weight221
Melting Point138.0 to 143.0 deg-C
Density1.42
TSCAYes
Boiling Point160
Vapor Pressure0.4 mmHg ( 160 °C)
Solubility略溶于水. 分解. 0.0890 G/100 ML
Stability对光敏感
Flash Point160°C/0.4mm
Appearance crystalline

别名和识别编码

Chemical Name2,4-Dichlorophenoxyacetic acid
Alfabeta NameDICHLOROPHENOXYACETICACID 24()-,
MDL NumberMFCD00004300
CAS Number94-75-7
Synonym Hedonal, herbicide Weed B Gon NSC 423 Foredex 75 Moxone AKOS BBS-00003746 {uni_hamburg} 2-(2,4-Dichlorophenoxy)acetic Acid 2,4-dichlorophenoxyacetic acid Ipaner 2,4-Dichlor-phenoxyessigsäure Amoxone Chloroxone IFLAB-BB F0850-6564 Barrage 'LGC' (130 Citrus f Acido(2,4-dicloro-fenossi)-acetico C (2,4-Dichlor-phenoxy)-essigsaeure Crotilin Fernoxone DED-WEED 2,4-D (IS Phenox Diclordon (2,4-Dichlorophe 2,4-D;2,4-二氯苯氧基乙酸;(2,4-二氯苯氧基)乙酸 Fernimine RARECHEM AL BO 0361 DMA-4 2,4-PA 2,4-D {h (2,4-Dichlorop
PubChem Substance ID1486
EC Number202-361-1
Beilstein Registry Number6(4)908
Reaxys-RN1214242
Merck Number2796
Chemical Name Translation2,4-二氯苯氧乙酸
Wiswesser Line NotationQV1OR BG DG
LabNetwork Molecule IDLN00132113
InChIInChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)
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分类

  • {SNA} Auxins, Plant Biotechnology, Plant Growth Regulators, 分子生物学, 植物组织培养
  • {SNA} A-D, All Herbicide Standards, Analytical Standards, D, Others, 农残和代谢标准品, 分析/色谱, 按照字母排序, 灭草剂
  • Auxins, Plant Biotechnology, Plant Growth Regulators, Plant Tissue Culture
  • {SA} Acid Halides, Building Blocks, Carbonyl Compounds, Chemical Synthesis, Organic Building Blocks
  • {SNA} Auxins, Molecular Biology, Plant Biotechnology, Plant Growth Regulators, Plant Tissue Culture
  • {SNA} All alphabetically sorted, Analytical Standards,
  • {SNA} A-D,
  • {SNA} A-D,

产品应用

  • 除草剂,植物生长剂,有机微量分析测定碳和氢的标准。

相关文献及参考

  • Merck: 14,2796 Beilstein:6(4)908
  • Way, J.M., et al.: Residue Rev., 26, 37 (1969),
  • Rowe, V.K., et al.: Am. J. Vet. Res., 15, 622 (1954),
  • Short: III/20b
  • Short: EINECS
  • Merck: 14,2796
  • Short: IV/8A

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard statements
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H318 Causes serious eye damage 严重伤害眼睛
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302+H332
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes
RTECSAG6825000
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P301+P312+P330
  • P302+P350
  • P308+P313
  • P403+P233
  • P305+P351+P338+P310
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P302+P352+P333+P313+P362+P364
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P304+P340+P312
  • P405 Store locked up. 上锁保管。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
Signal word
UN Number 2765 UN 3077 9/PG 3 3077
Safety Statements
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时,立即求医并出示容器/标签;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R11 Highly flammable 非常易燃
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R52/53
  • R37 Irritating to respiratory system 刺激呼吸道
  • R22 Harmful if swallowed 吞咽有害
Packing GroupIII
Storage condition APPROX 4°C 2-8°C避光保存。 储存温度2-8℃ ,避光保存。
Hazard Class9
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMPMAR Archives des Maladies Professionnelles de Medecine du Travail et de
   Securite Sociale.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.7-    1946-
   Volume(issue)/page/year: 12,26,1951

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE

{haz

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 347 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPZHAW Roczniki Panstwowego Zakladu Higieny.  (Ars Polona, POB 1001, 00-068
   Warsaw 1, Pol

TYPE OF TEST            : LDLo - Lowest published

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   48,A192,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 5714 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - change in rate
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   66,518,1992

{hazar

{ha

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5 mg/disc
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB80-133226

TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 55,197,1978

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 4 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands)

TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 10 ppb
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volu

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 204,615,1988

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 167 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   10(Suppl 10),1,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 500 mg/kg
SEX/DURATION            : female 6-15 da

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 125 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 9,801,1971

TYPE OF TEST            : TDLo - Lowe

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXP

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 gm/kg
SEX/DURATION            : female 15-24 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   NETEEC Neurotoxicology and Teratology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.9-    1987- Volume(issue)/page/year:
   18,691,1996

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 900 mg/kg
SEX/DURATION            : female 6-14 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
   before birth)
   Reproductive - Effects on Embryo or Fetus - extra-embryonic structures
   (e.g., placenta, umbilical cord)
   Reproductive - Specific Developmental Abnormalities - eye/ear
REFERENCE :
   NTIS** National Technical Informa

其他信息

  • 图谱信息:2,4-二氯苯氧乙酸(94-75-7)质谱(MS) 2,4-二氯苯氧乙酸(94-75-7)核磁图( 13 CNMR) 2,4-二
  • Acros Organics:2,4-二氯苯氧基乙酸/2,4-滴 2,4-Dichlorophenoxyacetic acid(94-75-7)
  • 2,4-二氯苯氧乙酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80047826 2,4-二氯苯氧基乙酸 100g 55元 2011/04/16 D0396 2,4-二氯苯氧基乙酸 2,4-Dichlorophenoxyacetic Acid 500G 1120元 2010/06/21 113635000 2,4-二氯苯氧乙酸 2,4-Dichlorophenox
  • {Chemical
  • MOL 文件:94-75-7.mol
  • 用途七:除草剂,植物生长剂,有机微量分析测定碳和氢的标准。
  • 方法二:由2,4-二氯苯酚与一氯乙酸在NaOH溶液中加热回流制得2,4-二氯苯氧乙酸钠,再用盐酸酸化而成。
  • 蒸气压:0.4 mm Hg ( 160 °C)
  • 急性毒性:口服- 大鼠 LD50: 375 毫克/ 公斤; 口服- 小鼠 LD50: 347 毫克/ 公斤
  • {Chemi
  • 方法三:以苯酚为原料,先与氯乙酸缩合后经氯化,或先氯化后与氯乙酸缩合均可制得产品。(1)先缩合后氯化工艺。将苯酚置于反应釜,加热熔融,先后投入2.2倍(摩尔比)地氢氧化钠和1.2倍(摩尔比)地氯乙酸,并在100-110℃下反应30min。反应物冷却后,用盐酸中和,可析出苯氧乙酸,收率82%以上。 苯氧乙酸于65-90℃下,缓慢通入1.4倍-1.6倍(摩尔比)地氯气,氯化产物即2,4-二氟苯氧乙酸,收率89%。 (2)先氯化后缩合工艺。将熔融的苯酚置于氯化器中,在45-65℃下通氯约8-9h,当反应物料相对密度达1.406(40℃)时氯化反应结束。反应物趁热加入30%的氢氧化钠溶液,加热至沸后,滴加氯乙酸钠溶液,并回流4-5h。稍冷后用30%的盐酸中和至PH1-3。趁热加苯萃取,并分出有机层。冷却后析出白色结晶,经抽滤、烘干得成品。
  • 外观性质:白色至黄色、晶体粉末、无臭、工业品略带酚气味。
  • 食品添加剂最大允许使用量最大允许残留量标准:添加剂中文名称 允许使用该种添加剂的食
  • 所属类别一:食品添加剂: 防腐杀虫剂: 防霉剂和保鲜剂
  • 方法一:以苯酚为原料,先与氯乙酸缩合后经氯化,或先氯化后与氯乙酸缩合均可制得产品。 先缩合后氯化工艺 将苯酚置于反应釜,加热熔融,先后投入2.2倍(摩尔比)的氢氧化钠和l.2倍(摩尔比)的氯乙酸,并在100~110℃下反应30min。反应物冷却后,用盐酸中和,可析出苯氧乙酸,收率82%以上。 苯氧乙酸于65~90℃下,缓慢通入1.4~1.6倍(摩尔比)的氯气,氯化产物即为2,4-二氯苯氧乙酸,收率89%。 先氯化后缩合工艺 将熔融的苯酚置于氯化器中,在45~65℃下通氯约8~9h,当反应物料相对密度达1.406
  • 海关编码:29189090
  • 上游原料:氢氧化钠 --> 苯酚 --> 氯乙酸 --> 氯乙酸钠 --> 2,4-二氯酚 --> 苯氧乙酸 --> 2,4-二氯苯氧乙酸钠 --> 2,4-D原药
  • color:off-white to tan
  • TCI Shanghai:(2,4-二氯苯氧基)乙酸 2,4-Dichlorophenoxyacetic Acid,>;97.0%(T)(94-75-7)
  • 刺激数据:皮肤- 兔子 500 毫克/ 24小时 轻度; 眼睛- 兔子 0.75 毫克/ 24小时 重度
  • 图谱信息:2,4-二氯苯氧乙酸(94-75-7)质谱(MS) 2,4-二氯苯氧乙酸(94-75-7)核磁图( 13 CNMR) 2,4-二氯苯氧乙酸(94-75-7)红外图谱(IR2) 2,4-二氯苯氧乙酸(94-75-7)核磁
  • 用途五:防腐保鲜剂。可与其他消毒剂等配伍使用。可有限防止柑橘类水果的蒂腐病。

系列性分类


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