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• 试剂商城
• 直接询价

分类

• Cancer Research, Cell Biology,
• {SNA} Growth Factors and Cytokines, HumanKine Growth Factors and Cytokines, 细胞培养, 试剂和添加剂
• {SNA} Growth Factors and Cytokines, HumanKine Growth Factors and Cytokines, Tumor Necrosis Factor (TNF) Superfamily, 细胞培养, 试剂和添加剂
• {S
• {SNA} Core Bioreagents, Cytokines Growth Factors and Hormones (Obesity), Cytokines and Growth Factors,

相关文献及参考

• Woodward, J.K.L., et al., Stimulation and Inhibition of Uveal Melanoma Invasion by HGF, GRO, IL-1{alpha} and TGF-{beta} Invest. Ophthalmol. Vis. Sci. 43 , 3144-52, (2002) 摘要
• Zhang, C., et al., TNF-{alpha} Suppresses Prolyl-4-Hydroxylase {alpha}1 Expression via the ASK1-JNK-NonO Pathway Arterioscler. Thromb. Vasc. Biol. 27 , 1760-7, (2007) 摘要
• Zhang, J., et al., S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF- Signaling through IKK2 J. Biol. Chem. 283 , 35375-82, (2008) 摘要
• Ware, C., et al., Thomson, A.W., ed., Tumor necrosis factor-related ligands and receptors. The Cytokine Handbook 3rd ed., San Diego, CA , (1998), 549
• Aggarwal, B., and Reddy, S., Nicola, N., ed., Tumor necrosis factor (TNF). Guidebook to Cytokines and Their Receptors New York , (1994), 103-104
• Callard, R., and Gearing, A. The Cytokine Facts Book New York , (1994)
• Beutler, B., Sporn, M., and Roberts, A, ed., Cachectin/tumor necrosis factor and lymphotoxin. Peptide Growth Factors and their Receptors II New York , (1991), 39-70
• Clemens, M. J., et al. Lymphokines and Interferons, A Practical Approach , (1994), 121

安全信息

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCBM British Journal of Pharmacology.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.34-    1968-  Volume(issue)/page/year:
   99,499,1990

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 ku/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 12,1355,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 100 ug/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 135,239,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 ku/kg
SEX/DURATION            : female 7 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 89,447,1990