CAS 95-76-1 MFCD00007768-3,4-Dichloroaniline 3,4-二氯苯胺 -LabNovo

3,4-Dichloroaniline 3,4-二氯苯胺

CAS 95-76-1 MFCD00007768

化学结构图

SMILES: Nc1ccc(Cl)c(Cl)c1

化学属性

Mol. Formula	C6H5Cl2N
Mol. Weight	162.02
Boiling Point	272
Melting Point	69-71
Density	1.401
Flash Point	135°(275°F)
TSCA	Yes
Solubility	0.06 G/100 ML

别名和识别编码

Chemical Name	3,4-Dichloroaniline
CAS Number	95-76-1
Alfabeta Name	DICHLOROANILINE 34-,
MDL Number	MFCD00007768
Synonym	3,4-Dichloraniline {LY} 3,4-Dichloraniline 3,4-DichloroAniline(3,4-Dca)99.5% 3,4-Dichloroanaline 3,4-Dichloroaniline 3,4-Dichloroaniline,>98% 3,4-Dichlorobenzenamine 3,4-Dichlorophenylamine 3,4-dca 3,4-dichloro-anilin 3,4-dichloro-aniline 3,4-dichloro-benzenamin 3,4-dichlorobenzenamine 3,4-dichlorophenylamine 3,4-二氯苯胺 3,4-二氯苯胺,98% 3.4-二氯苯胺 {} {LY} 3,4-Dichloraniline {} {} {LY} 3,4-Dichloraniline {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {} {} { {} {} {} {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Dichloraniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 3,4-Dichloraniline {} {}
PubChem Substance ID	87567017
EC Number	202-448-4
Beilstein Registry Number	636837
Reaxys-RN	636837
Merck Number	3054
Chemical Name Translation	3,4-二氯苯胺
Wiswesser Line Notation	ZR CG DG
LabNetwork Molecule ID	LN00173903
InChI	InChI=1S/C6H5Cl2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2
Canonical SMILES	NC1=CC=C(Cl)C(Cl)=C1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

可作农药和染料的中间体。用于合成敌稗、利谷隆、敌草隆、灭草灵等除草剂及偶氮染料。也用作生物活性组分中间体。

安全信息

Warnings 危化品目录(2015) IRRITANT

GHS Symbol

WGK Germany3

Hazard statements

H302 Harmful if swallowed 吞食有害
H331 Toxic if inhaled 吸入中毒
H311 Toxic in contact with skin 皮肤接触中毒
H301 Toxic if swallowed 吞食有毒
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
H318 Causes serious eye damage 严重伤害眼睛
H317 May cause an allergic skin reaction 可能导致皮肤过敏

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes T,N

RTECSBX2625000

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338
P332+P313
P501 Dispose of contents/container to..… 处理内容物/容器.....
P301+P312+P330
P302+P350
P403+P233
P305+P351+P338+P310
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P304+P340+P311
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
P273 Avoid release to the environment. 避免释放到环境中。
P308+P311
P301+P310
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P302+P352+P312+P361+P364
P405 Store locked up. 上锁保管。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。

Signal word

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Risk Statements

R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
R50/53
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

UN Number UN3442 UN 3442 6.1/PG 2

Packing GroupII

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

Hazard Class6.1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 237 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 12,355,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 675 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 280 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   LPPTA

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 200 mg/L
REFERENCE :
   CJMIAZ Canadian Journal of Microbiology.  (National Research Council of
   Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.1- 
     1954-  Volume(issue)/page/year: 16,369,1970

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 125 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 226,197,1989

Restrict 危险品

其他信息

TCI Shanghai:3,4-二氯苯胺 3,4-Dichloroaniline,>;98.0%(GC)(95-76-1)
用途一:用作医药、农药、染料的中间体
毒性分级:中毒
刺激数据:皮肤-兔子2 毫克/24小时重度; 眼睛-兔子 0.25 毫克/24小时重度
急性毒性:口服-大鼠 LD50: 545 毫克/公斤 ;口服-小鼠 LD50: 740 毫克/公斤
Sigma Aldrich:95-76-1(sigmaaldrich)
储运特性:库房通风低温干燥; 与氧化剂、食品添加剂、酸类分开存放
可燃性危险特性:明火可燃燃烧释放有毒氯化物, 氮氧化物烟雾
类别:有毒物品
防护措施:有毒。能引起呼吸系统、神经系统及造血系统的病变。小鼠灌胃LD50为1000mg/kg，大鼠灌胃LD50为700mg/kg。大鼠的嗅觉阈0.047mg/m3；眼睛光感最低0.025mg/kg。设备应密闭，防止跑、冒、滴、漏。操作时应穿戴防护用具，避免与人体直接接触。操作场所空气中最高容许浓度0.05mg/m3。
图谱信息:3,4-二氯苯胺(95-76-1)核磁图( 1 HNMR) 3,4-二氯苯胺(95-76-1)核磁图( 13 CNMR) 3,4-二氯苯胺(95-76-1)红外图谱(IR2) 3,4-二氯苯胺(95-76-1)红外图谱(IR1) 3
用途三:可作农药和染料的中间体。用于合成敌稗、利谷隆、敌草隆、灭草灵等除草剂及偶氮染料。也用
MSDS 信息:3,4-二氯苯胺(95-76-1).msds
防护措施:有毒。能引起呼吸系统、神经系统及造血系统的病变。小鼠灌胃LD50为1000mg/kg，大鼠灌胃LD50为700mg/kg。大鼠的嗅觉阈0.047mg/m3；眼睛光
用途二:3，4-二氯苯胺是除草剂敌稗、敌草隆、利谷隆、草不隆等的中间体。
上游原料:氯 --> 氢 --> 三氯化铁 --> 邻二氯苯 --> 4-硝基氯苯 --> 工业乙醇 --> 3,4-二氯硝基苯
Alfa Aesar:3,4-二氯苯胺,98% 3,4-Dichl
下游产品:3,4-二氯-N-甲基苯胺 --> 敌稗 --> 敌草隆 --> 1-(3,4-二氯苯基)哌嗪 --> 3,4-二氯苯异氰酸酯 --> 2-氨基-5,6-二氯苯甲酸 --> 灭草灵 --> 5-[(3,4-二氯苯)偶氮基]-1,2-二氢-6-羟基-1,4-二甲基-2-氧代-3
存储注意事项:光敏感
外观性质:褐色针状结晶。
海关编码:29214210
Acros Organics:3,4-二氯苯胺 3,4-Dichloroaniline, 98%(95-76-1)
方法一:其制备方法是在反应釜中加入对氯硝基苯、无水三氯化铁催化剂，于100～110℃通入氯气，当测定氯化反应物凝固点到30～31℃时即为反应终点。将此物移至还原釜，再加入硫代硫酸钠(以消除反应物中剩余氯的影响)、甲酸，加热到100℃(回流状态)慢慢加入铁粉(约4～5h加完)，而后继续保持回流反应，当观察不到硝基苯存在时即为反应终点。加入3，4-二氯苯胺产量5～6倍的氯苯，搅拌0.5～1.0 h，经冷却、过滤并以少量氯苯洗涤滤渣，所得滤液为3，4-二氯苯胺的氯苯溶液，加热脱氯苯得3，4-二氯苯胺。也可以用3，4-二氯硝基苯催化加氢而制得。在高压釜中加入3，4-二氯硝基苯，并加入兰尼镍催化剂，工业乙醇为溶剂，用氮气赶高压系统3次，氢气赶3次，然后充氢气达压力为4 MPa，同时升温至60～70℃进行反应，直到不吸收氢气为止，然后冷却经后处理可得成品。此外，也可用邻二氯苯为原料，经硝化得3，4-二氯硝基苯，再进一步还原得成品。国外大部分企业用此法生产3，4-二氯苯胺。
MOL 文件:95-76-1.mol
常规方法:用铁桶包装，一般自用。以铁罐贮存，泵输送。

3,4-Dichloroaniline 3,4-二氯苯胺

CAS 95-76-1 MFCD00007768

化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

系列性分类

相关产品推荐

Products Indices

Mailings

Contact

链接

搜索结果

化学结构图

化学属性

别名和识别编码

分类

产品应用

相关文献及参考

安全信息

其他信息

系列性分类

相关产品推荐

Products Indices

Mailings

Contact

链接