(2S,3aS,7aS)-1-((S)-2-(((S)-1-Carboxybutyl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid 培哚普利

CAS 95153-31-4 MFCD95153314

化学结构图

95153-31-4
SMILES: C[C@H](N[C@@H](CCC)C(O)=O)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O

化学属性

Mol. Weight340.47
Mol. FormulaC17H28N2O5

别名和识别编码

CAS Number95153-31-4
Chemical Name(2S,3aS,7aS)-1-((S)-2-(((S)-1-Carboxybutyl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid
Synonym [2S-[1[R*(R*)],2?,3a?,7a?]]-1-[2-[(1-Carboxybutyl)amino]-1- Perindoprilat S 9780 (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxybutyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid
Beilstein Registry Number4207072
Chemical Name Translation培哚普利
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分类

  • Amines
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive.

相关文献及参考

  • Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)

安全信息

RTECSNL6007250 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   10,446,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   10,446,1992

系列性分类

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