(R)-Pramipexole Dihydrochloride 普拉克索杂质E
CAS 104632-28-2 MFCD04632282
化学结构图
SMILES: CCCN[C@H]1CC2SC(N)=NC=2CC1
化学属性
| Mol. Weight | 284.25 |
|---|---|
| Mol. Formula | C10H19Cl2N3S |
别名和识别编码
| CAS Number | 104632-28-2 |
|---|---|
| Chemical Name | (R)-Pramipexole Dihydrochloride |
| Synonym | (R)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine Dihydrochloride R-(+)-Pramipexole Dihydrochloride |
| Chemical Name Translation | 普拉克索杂质E |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Chiral Reagents
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
- The opposite enantiomer of Pramipexole (P700755),
相关文献及参考
- [2]. Alavian KN, Dworetzky SI, Bonanni L, et al. Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency. Brain Res. 2012 Mar 29;1446:1-11.
- [3]. Cudkowicz M, Bozik ME, Ingersoll EW, et al. The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med. 2011 Nov 20;17(12):1652-6.
- [4]. Bozik ME, Mather JL, Kramer WG, et al. Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects. J Clin Pharmacol. 2011 Aug;51(8):1177-85.
- [5]. Cheah BC, Kiernan MC. Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Dec;13(12):911-20.
- Mierau, J., et al.: J. Med. Chem., 30, 494 (1987),
- Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992),
- [1]. Rudnicki SA, Berry JD, Ingersoll E, et al. Dexpramipexole effects on functional decline and survi
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