N-(4-Chloro-3-Methoxyphenyl)Picolinamide N-(4-氯-3-甲氧基苯基)-2-吡啶甲酰胺

CAS 1161205-04-4 MFCD261205044

化学结构图

1161205-04-4
SMILES:

化学属性

Mol. FormulaC13H11CIN2O2

别名和识别编码

Chemical NameN-(4-Chloro-3-Methoxyphenyl)Picolinamide
Chemical Name TranslationN-(4-氯-3-甲氧基苯基)-2-吡啶甲酰胺
Chemicalbook IDCB62518798
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相关文献及参考

  • [2]. Engers DW, et al. Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in rats. J Med Chem. 2011 Feb 24;54(4):1106-10.
  • [3]. Jantas D, et al. Neuroprotective effects of mGluR II and III activators against staurosporine- and doxorubicin-induced cellular injury in SH-SY5Y cells: New evidence for a mechanism involving inhibition of AIF translocation. Neurochem Int. 2015 Sep;88:124-37.
  • [1]. Engers DW, et al. Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric mo
  • [1]. Engers DW, et al. Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). J Med Chem. 2009 Jul 23;52(14):4115-8.

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