(R,E)-2-Amino-3-(1H-Indol-3-Yl)-N’-(Quinoxalin-6-Ylmethylene)Propanehydrazide Hydrochloride (R,E)-2-氨基-3-(1H-吲哚-3-基)-N’-(喹喔啉-6-基亚甲基)丙酰肼盐酸盐

CAS 1281870-42-5 MFCD381870425

化学结构图

1281870-42-5
SMILES: Cl.NC(Cc1c[nH]c2ccccc12)C(=O)NN=Cc1ccc2nccnc2c1

别名和识别编码

PubChem Substance ID52998412
InChIInChI=1S/C20H18N6O.ClH/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18;/h1-9,11-12,16,24H,10,21H2,(H,26,27);1H/b25-11+;/t16-;/m1./s1
Chemical Name Translation(R,E)-2-氨基-3-(1H-吲哚-3-基)-N’-(喹喔啉-6-基亚甲基)丙酰肼盐酸盐
Chemical Name(R,E)-2-Amino-3-(1H-Indol-3-Yl)-N’-(Quinoxalin-6-Ylmethylene)Propanehydrazide Hydrochloride
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相关文献及参考

  • [2]. Shang X, et al. Small-molecule inhibitors targeting G-protein-coupled Rho guanine nucleotide exchange factors. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3155-60.
  • [3]. Francis TC, et al. The Selective RhoA Inhibitor Rhosin Promotes Stress Resiliency Through Enhancing D1-Medium Spiny Neuron Plasticity and Reducing Hyperexcitability. Biol Psychiatry. 2019;85(12):1001-1010.
  • [1]. Shang X, et al. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol. 2012 Jun 22;19(6):699-710.
  • [1]. Shang X, et al. Rational design of small molecule inhibitors targeting RhoA subfamily Rho GTPases. Chem Biol. 2012 Jun 22;19(6):699-710.
  • [2]. Shang X, et al. Small-molecule inhibitors targeting G-protein-coupled Rho guanine nucleotide exchange factors. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3155-60.
  • [3]. Francis TC, et al. The Selective RhoA Inhibitor Rhosin Promotes Stress Resiliency Through Enhancing D1-Medium

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Ras  (Ras蛋白)

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