16α-Methyl-9,11-dehydro Prednisolone
CAS 13209-41-1 MFCD13209411
化学结构图
SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3=CC[C@]2(C)[C@@]1(O)C(=O)CO |&1:1,3,4,13,18,20|
化学属性
| Mol. Weight | 356.46 |
|---|---|
| Mol. Formula | C22H28O4 |
别名和识别编码
| CAS Number | 13209-41-1 |
|---|---|
| Chemical Name | 16α-Methyl-9,11-dehydro Prednisolone |
| Synonym | (16?)-17,21-Dihydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione 17?,21-Dihydroxy-16?-methylpregna-1,4,9(11)-triene-3,20-dione |
| Chemical Name Translation |
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分类
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Steroids
产品应用
- A related intermediate of Prednisolone (P703740).
相关文献及参考
- [2]. Dillingham BC, et al. VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis. Cell Mol Neurobiol. 2015 Apr;35(3):377-387.
- [3]. Heier CR, et al. Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy. Life Sci Alliance. 2019 Feb 11;2(1). pii: e201800186.
- Cimarusti, C., et al.: J. Med. Chem., 19, 721 (1976),
- Popper, T., et al.: J. Steroid Biochem., 27, 837 (1987),
- [1]. Heier CR, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. EMBO Mol Med. 2013 Oct;5(10):1569-85.
- [1]. Heier CR, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. EMBO Mol Med. 2013 Oct;5(10):1569-85.
- [2]. Dillingham BC, et al. VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimm
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