Frovatriptan Succinate Monohydrate 罗曲普坦琥珀酸盐

CAS 158930-17-7 MFCD58930177

化学结构图

158930-17-7
SMILES: CN[C@@H]1CCC2NC3C=CC(=CC=3C=2C1)C(N)=O.OC(=O)CCC(O)=O

化学属性

Mol. Weight379.41
Mol. FormulaC18H25N3O6

别名和识别编码

CAS Number158930-17-7
Chemical NameFrovatriptan Succinate Monohydrate
Synonym (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide Butanedioic Acid Monohydrate Frova Frovelan Migard Miguard
Chemical Name Translation罗曲普坦琥珀酸盐
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分类

  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.

相关文献及参考

  • [2]. Comer MB. Et al. Pharmacology of the selective 5-HT(1B/1D) agonist frovatriptan. Headache. 2002 Apr;42 Suppl 2:S47-53.
  • Parsons, A.A., et al.: J. Cardiovasc. Pharmacol., 30, 136 (1997),
  • Poolsup, N., et al.: J. Clin. Pharm. Ther., 30, 521 (2005),
  • Siow, C.H., et al.: Cephalalgia, 24, 1045 (2004),
  • [1]. Kelman L. Review of frovatriptan in the treatment of migraine. Neuropsychiatr Dis Treat. 2008 Feb;4(1):49-54.
  • [1]. Kelman L. Review of frovatriptan in the treatment of migraine. Neuropsychiatr Dis Treat. 2008 Feb;4(1):49-54.
  • [2]. Comer MB. Et al. Pharmacology of the selective 5-HT(1B/1D) agonist frovatriptan. Headache. 2002 Apr;42 Suppl 2:S47-53.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)

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