3-((3R,4R)-4-Methyl-3-(Methyl(6-Oxo-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Piperidin-1-Yl)-3-Oxopropanenitrile 3-((3R,4R)-4-甲基-3-(甲基(6-氧代-6,7-二氢-5H-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈

CAS 1640971-51-2 MFCD740971512

化学结构图

1640971-51-2
SMILES:

别名和识别编码

Chemical Name3-((3R,4R)-4-Methyl-3-(Methyl(6-Oxo-6,7-Dihydro-5H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)Amino)Piperidin-1-Yl)-3-Oxopropanenitrile
Chemical Name Translation3-((3R,4R)-4-甲基-3-(甲基(6-氧代-6,7-二氢-5H-吡咯并[2,3-d]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈
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相关文献及参考

  • [2]. Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.
  • [1]. Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73.
  • [1]. Martin E Dowty, et al. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans. Drug Metab Dispos. 2014 Apr;42(4):759-73.
  • [2]. Matthias Gehringer, et al. Novel Hinge-Binding Motifs for Janus Kinase 3 Inhibitors: A Comprehensive Structure-Activity Relationship Study on Tofacitinib Bioisosteres. ChemMedChem. 2014 Nov;9(11):2516-27.

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Drug Metabolite  (药物代谢物)

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