Phosphoramidon disodium salt

CAS 164204-38-0 MFCD64204380

化学结构图

164204-38-0
SMILES: CC(C)C[C@H](NP(O)(=O)O[C@@H]1O[C@@H](C)[C@@H](O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](CC1=CNC2C=CC=CC=21)C(O)=O

别名和识别编码

Chemical Name Translation
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相关文献及参考

  • [2]. Sun Q, et al. Synthesis and enzymatic evaluation of phosphoramidon and its β anomer: Anomerization of α-l-rhamnose triacetate upon phosphitylation.Bioorg Med Chem. 2013 Nov 1;21(21):6778-87.
  • [3]. Hanson LR, et al. Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice.J MolNeurosci. 2011 Mar;43(3):424-7.
  • [4]. Bhavsar TM, et al. Phosphoramidon, an endothelin-converting enzyme inhibitor, attenuates lipopolysaccharide-induced acute lung injury.Exp Lung Res. 2008 Mar;34(3):141-54.
  • [5]. Matsumaru K, et al. Phosphoramidon, an inhibitor of endothelin-converting enzyme, prevents indomethacin-induced gastric mucosal damage in rats.Life Sci. 1998;62(7):PL79-84.
  • [1]. Kukkola PJ, et al. Differential structure-activity relationships of phosphoramidon analogues for inhibition of three metalloproteases: endothelin-converting enzyme, neutral endopeptidase, and angiotensin-converting enzyme.J CardiovascPharmaco

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Angiotensin-converting Enzyme (ACE)  (血管紧张素转换酶)
  1. Medical Research Areas
  2. Metabolism
  3. Neprilysin  (脑啡肽酶)

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