Sr144528 5-(4-氯-3-甲基苯基)-1-[(4-甲基苯基)甲基]-N-[(1R,3S,4S)-2,2,4-三甲基-3-双环[2.2.1]庚基]吡唑-3-甲酰胺

CAS 192703-06-3 MFCD92703063

化学结构图

192703-06-3
SMILES: CC1(C)[C@@H](NC(=O)C2C=C(C3=CC(C)=C(Cl)C=C3)N(CC3C=CC(C)=CC=3)N=2)[C@]2(C)C[C@H]1CC2 |&1:3,28,31|

化学属性

Mol. Weight417
Mol. FormulaC30H44D6

别名和识别编码

Chemical NameSr144528
CAS Number192703-06-3
Chemical Name Translation5-(4-氯-3-甲基苯基)-1-[(4-甲基苯基)甲基]-N-[(1R,3S,4S)-2,2,4-三甲基-3-双环[2.2.1]庚基]吡唑-3-甲酰胺
MDL Number
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相关文献及参考

  • [2]. Thewke D, et al. AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors. Biochem Biophys Res Commun. 2009 Apr 3;381(2):181-6.
  • [3]. Abalo R, et al. The cannabinoid antagonist SR144528 enhances the acute effect of WIN 55,212-2 on gastrointestinal motility in the rat. Neurogastroenterol Motil. 2010 Jun;22(6):694-e206.
  • [1]. Rinaldi-Carmona M, et al. SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor. J Pharmacol Exp Ther. 1998 Feb;284(2):644-50.
  • [1]. Rinaldi-Carmona M, et al. SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor. J Pharmacol Exp Ther. 1998 Feb;284(2):644-50.
  • [2]. Thewke D, et al. AM-251 and SR144528 are acyl CoA:cholesterol acyltransferase inhibitors. Biochem Biophys Res Commun. 2009 Apr 3;381(2):181-6.
  • [3]. Abalo R, et al. The cannabinoid antagonist SR144528 enhances the acute effect of WIN 55,212-2 on gastrointestinal motility in the

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Cannabinoid Receptor  (大麻素受体)

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