Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynoma with evidence of preclinical antitumor activity. Phase I clinical trial results: Dose level VIII (200 mg/m(2)) was considered the MTD, and dose level IX (160 mg/m(2)) was defined as the RD. Limited antitumor activity was observed.

CAS 196497-48-0 MFCD96497480

化学结构图

196497-48-0
SMILES: CCCCCCCCCCCCCCCC(O)[C@@H](C)N

化学属性

Mol. Weight285.51
Appearance Solid powder
SolubilitySoluble in DMSO, not in water

别名和识别编码

Chemical NameSpisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynoma with evidence of preclinical antitumor activity. Phase I clinical trial results: Dose level VIII (200 mg/m(2)) was considered the MTD, and dose level IX (160 mg/m(2)) was defined as the RD. Limited antitumor activity was observed.
FormulaC18H39NO
Synonym ES285; ES285; Spisulosine .
IUPAC Name(2R)-2-aminooctadecan-3-ol
InChIKeyYRYJJIXWWQLGGV-QNSVNVJESA-N
InChIInChI=1S/C18H39NO/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17(2)19/h17-18,20H,3-16,19H2,1-2H3/t17-,18?/m1/s1
Canonical SMILESC[C@@H](N)C(O)CCCCCCCCCCCCCCC
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

产品应用

  • Spisulosine, also known as ES-285, is novel compound derived from the marine mollusk Spisula polynoma with evidence of preclinical antitumor activity. Phase I clinical trial results: Dose level VIII (200 mg/m(2)) was considered the MTD, and dose level IX (160 mg/m(2)) was defined as the RD. Limited antitumor activity was observed.

安全信息

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

系列性分类

  1. Medical Research Areas
  2. MARK
  3. JNK

相关产品推荐