4-(2-(3-(4-Nitrophenyl)-5-Oxo-1-Phenyl-1H-Pyrazol-4(5H)-Ylidene)Hydrazinyl)Benzenesulfonic Acid 4-(2-(3-(4-硝基苯基)-5-氧代-1-苯基-1H-吡唑-4(5H)-亚基)肼基)苯磺酸

CAS 314291-83-3 MFCD N/A

化学结构图

314291-83-3
SMILES:

化学属性

Mol. Weight465.44 (anhydrous free acid basis)
Mol. FormulaC21H15N5O6S · xNa+· yH2O

别名和识别编码

Synonym 4-[2-[1,5-dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-benzenesulfonic acid sodium salt hydrate
Chemical Name4-(2-(3-(4-Nitrophenyl)-5-Oxo-1-Phenyl-1H-Pyrazol-4(5H)-Ylidene)Hydrazinyl)Benzenesulfonic Acid
PubChem Substance ID329819990
CAS Number314291-83-3 (free acid)
Chemical Name Translation4-(2-(3-(4-硝基苯基)-5-氧代-1-苯基-1H-吡唑-4(5H)-亚基)肼基)苯磺酸
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, P-PH, PHPS1, Tyrosine Phosphatase Biology, Tyrosine Phosphatase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Jia Chen, et al. SHP2 Inhibitor PHPS1 Protects Against Atherosclerosis by Inhibiting Smooth Muscle Cell Proliferation. BMC Cardiovasc Disord. 2018 Apr 27;18(1):72.
  • [1]. Klaus Hellmuth, et al. Specific Inhibitors of the Protein Tyrosine Phosphatase Shp2 Identified by High-Throughput Docking. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7275-80.
  • [1]. Klaus Hellmuth, et al. Specific Inhibitors of the Protein Tyrosine Phosphatase Shp2 Identified by High-Throughput Docking. Proc Natl Acad Sci U S A. 2008 May 20;105(20):7275-80.
  • [2]. Jia Chen, et al. SHP2 Inhibitor PHPS1 Protects Against Atherosclerosis by Inhibiting Smooth Muscle Cell Proliferation. BMC Cardiovasc Disord. 2018 Apr 27;18(1):72.

安全信息

WGK Germany2

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Phosphatase  (磷酸酶)

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