(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-Yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[A]Phenanthrene-3,6,12-Triol (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-((S)-2-羟基-6-甲基庚-5-烯-2-基)-4,4,8,10,14-五甲基十六氢-1H-环戊[a]菲-3,6,12-三醇

CAS 34080-08-5 MFCD34080085

化学结构图

34080-08-5
SMILES:

化学属性

Mol. FormulaC30H52O4
Mol. Weight476.7300

别名和识别编码

Chemical Name(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-((S)-2-Hydroxy-6-Methylhept-5-En-2-Yl)-4,4,8,10,14-Pentamethylhexadecahydro-1H-Cyclopenta[A]Phenanthrene-3,6,12-Triol
Synonym 原人参三醇
Chemical Name Translation(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-17-((S)-2-羟基-6-甲基庚-5-烯-2-基)-4,4,8,10,14-五甲基十六氢-1H-环戊[a]菲-3,6,12-三醇
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相关文献及参考

  • [2]. Oh GS, et al. 20(S)-protopanaxatriol inhibits liver X receptor α-mediated expression of lipogenic genes in hepatocytes. J Pharmacol Sci. 2015 Jun;128(2):71-7.
  • [3]. Huang Q, et al. Co-administration of 20(S)-protopanaxatriol (g-PPT) and EGFR-TKI overcomes EGFR-TKI resistance by decreasing SCD1 induced lipid accumulation in non-small cell lung cancer. J Exp Clin Cancer Res. 2019;38(1):129. Published 2019 Mar 15.
  • [1]. Leung KW, et al. Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol. 2009 Feb;156(4):626-37.
  • [1]. Leung KW, et al. Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol. 2009 Feb;156(4):626-37.
  • [2]. Oh GS, et al. 20(S)-protopanaxatriol inhibits liver X receptor α-mediated expression of lipogenic genes in hepatocytes. J Pharmacol Sci. 2015 Jun;128(2):71-7.
  • [3]. Huang Q, et al. Co-admini

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Glucocorticoid Receptor  (糖皮质激素受体)
  1. Medical Research Areas
  2. Metabolism
  3. LXR  (肝X受体)

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