Gant 61 2,2'-[[二氢-2-(4-吡啶基)-1,3(2H,4H)-嘧啶二基]二(亚甲基)]二[N,N-二甲基苯胺]

CAS 500579-04-4 MFCD00579044

化学结构图

500579-04-4
SMILES:

化学属性

Mol. Weight429.60
Mol. FormulaC27H35N5

别名和识别编码

Synonym 2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine NSC 136476 NSC 136476
CAS Number500579-04-4
Chemical NameGant 61
Chemical Name Translation2,2'-[[二氢-2-(4-吡啶基)-1,3(2H,4H)-嘧啶二基]二(亚甲基)]二[N,N-二甲基苯胺]
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分类

  • Angiogenic Factors, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, Sonic Hedgehog
  • {SNA} Angiogenic Factors, Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, G, Sonic Hedgehog, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • Desch, P., et al., Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells. Jul 5.(Paracelsus Medical University) Oncogene Jul 5 , (2010)
  • Guan, C.C., et al., Sonic hedgehog alleviates the inhibitory effects of high glucose on the osteoblastic differentiation of bone marrow stromal cells. Bone 45 , 1146-1152, (2009) 摘要
  • Lauth, M., et al., Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists. Proc. Natl. Acad. Sci. U. S. A. 104 , 8455-8460, (2007) 摘要

安全信息

WGK Germany3
GHS Symbol

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Cytokines and Growth Factors - Cytokines, Growth Factors and Hormones
  6. Angiogenic Factors - Cytokines and Growth Factors
  7. Sonic Hedgehog - Angiogenic Factors

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