CAS 515814-01-4 MFCD15814014-Voclosporin -LabNovo

SMILES: CC(=O)OC(C(C(=O)CCCCCCC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC)C(C)C)N(C)C)[C@H](C)C/C=C/C=C |&1:16,20,33|

Mol. Weight	1,214.62
Mol. Formula	C63H111N11O12

CAS Number	515814-01-4
Chemical Name	Voclosporin
Synonym	6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A ISATX 247 R 1524 trans-ISA 247

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[2]. Stalder M, et al. In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates. J Heart Lung Transplant. 2003 Dec;22(12):1343-52.
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Cho, M., et al.: Arthritis Rheum., 46, 1202 (2002),
Staatz, C., et al.: Clin. Pharmacokinet., 43, 623 (2004),
[1]. Abel MD, et al. ISATX247: a novel calcineurin inhibitor. J Heart Lung Transplant. 2001 Feb;20(2):161.
[1]. Abel MD, et al. ISATX247: a novel calcineurin inhibitor. J Heart Lung Transplant. 2001 Feb;20(2):161.
[2]. Stalder M, et al. In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates. J Heart Lung Transplant. 2003 Dec;22(12):1343-52.

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