Descarbamoyl Cefuroxime

CAS 56271-94-4 MFCD56271944

化学结构图

56271-94-4
SMILES: CO/N=C(/C1=CC=CO1)\C(=O)N[C@@H]1[C@@H]2SCC(CO)=C(C(O)=O)N2C1=O |&1:12,13|

化学属性

Mol. Weight381.36
Mol. FormulaC15H15N3O7S

别名和识别编码

CAS Number56271-94-4
Chemical NameDescarbamoyl Cefuroxime
Synonym (6R,7R)-7-[[(2Z)-2-(2-Furanyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
Chemical Name Translation
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分类

  • Heterocycles
  • Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • A degradation product of Cefuroxime, and an intermediate for the synthesis of Cephalosporin antibiotics

相关文献及参考

  • [2]. Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[(Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acids. J Antibiot (Tokyo). 1981 Oct;34(10):1300-10.
  • Nomura, H., et al.: J. Med. Chem., 17, 12 (1974),
  • Takaya, T., et al.: J. Antibiotics, 34, 1300 (1981),
  • Wang, D., et al.: J. Pharm. Sci., 83, 577 (1994),
  • [1]. Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30(6-8):371-374.
  • [1]. Vercheval C, et al. Stability of 90 mg/mL cefuroxime sodium solution for administration by continuous infusion. J Chemother. 2018 Oct - Dec;30(6-8):371-374.
  • [2]. Takaya T, et al. Studies on beta-lactam antibiotics. III. Synthesis and enzymatic stability of 3-acyloxymethyl-7 beta-[(Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acids. J Antibi

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Drug Metabolite  (药物代谢物)

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