Sitagliptin phosphate 磷酸西他列汀
CAS 654671-78-0 MFCD54671780
化学结构图
SMILES: N[C@@H](CC(=O)N1CC2=NN=C(N2CC1)C(F)(F)F)CC1C=C(F)C(F)=CC=1F
化学属性
| Mol. Weight | 505.31 |
|---|---|
| Mol. Formula | C16H18F6N5O5P |
别名和识别编码
| CAS Number | 654671-78-0 |
|---|---|
| Chemical Name | Sitagliptin phosphate |
| Synonym | 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate |
| Chemical Name Translation | 磷酸西他列汀 |
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分类
- Aromatics
- Chiral Reagents
- Heterocycles
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
相关文献及参考
- Kim, D., et al.: J. Med. Chem. 48, 141 (2005),
- Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005),
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