Benzeneacetic acid,4-[[4-[(aminoiminomethyl)- amino]benzoyl]oxy]-,monomethanesulfonate 4-[[4-[(氨基亚氨基甲基)-氨基]苯甲酰基]氧基]-苯乙酸单甲磺酸盐

CAS 71079-09-9 MFCD71079099

化学结构图

71079-09-9
SMILES: CS(O)(=O)=O.NC(=N)NC1C=CC(=CC=1)C(=O)OC1C=CC(CC(O)=O)=CC=1

化学属性

Mol. Weight409.41
Mol. FormulaC17H19N3O7S

别名和识别编码

CAS Number71079-09-9
Chemical NameBenzeneacetic acid,4-[[4-[(aminoiminomethyl)- amino]benzoyl]oxy]-,monomethanesulfonate
Synonym 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate
Chemical Name Translation4-[[4-[(氨基亚氨基甲基)-氨基]苯甲酰基]氧基]-苯乙酸单甲磺酸盐
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分类

  • Amine
  • Aromatics
  • Inhibitors
  • Metabolites & Impurities

产品应用

  • A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy.

相关文献及参考

  • [2]. Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertension. J Hypertens . 2009 Jan;27(1):181-9.
  • [3]. Markus Hoffmann, et al. Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. bioRxiv. 2020 Aug 5;2020.08.05.237651.
  • Senochuki, K., et al.: J. Med. Chem., 38, 2521 (1995)
  • [1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6.
  • [1]. K Beckh, et al. Elimination of the Low-Molecular Weight Proteinase Inhibitor Camostate (FOY 305) and Its Degradation Products by the Rat Liver. Res Exp Med (Berl). 1987;187(6):401-6.
  • [2]. Ai Maekawa, et al. Camostat Mesilate Inhibits Prostasin Activity and Reduces Blood Pressure and Renal Injury in Salt-Sensitive Hypertens

系列性分类

  1. Medical Research Areas
  2. Metabolism
  3. Ser/Thr Protease  (丝氨酸/苏氨酸蛋白酶)

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