(2R,3R)-3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride 反式-3-(异丙基氨基)-1-((7-甲基-2,3-二氢-1H-茚-4-基)氧基)丁烷-2-醇盐酸盐

CAS 72795-01-8 MFCD N/A

化学结构图

72795-01-8
SMILES: CC1C=CC(OC[C@@H](O)[C@@H](C)NC(C)C)=C2CCCC=12 |&1:7,9|

化学属性

Mol. Weight313.86
Mol. FormulaC17H28ClNO2

别名和识别编码

CAS Number72795-01-8
Chemical Name(2R,3R)-3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride
Synonym (2R,3R)-rel-
Chemical Name Translation反式-3-(异丙基氨基)-1-((7-甲基-2,3-二氢-1H-茚-4-基)氧基)丁烷-2-醇盐酸盐
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分类

  • Aromatics
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • The (R,R)-enantiomer

相关文献及参考

  • [2]. Wenzel D, et al. beta(2)-adrenoceptor antagonist ICI 118,551 decreases pulmonary vascular tone in mice via a G(i/o) protein/nitric oxide-coupled pathway. Hypertension. 2009 Jul;54(1):157-63.
  • [3]. Gong H, et al. Specific beta(2)AR blocker ICI 118,551 actively decreases contraction through a G(i)-coupled form of the beta(2)AR in myocytes from failing human heart. Circulation. 2002 May 28;105(21):2497-503.
  • [4]. Hoffmann C, et al. Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol. 2004 Feb;369(2):151-9.
  • Bilski, A., et al.: J. Cardiovasc. Pharmacol., 5, 430 (1983),
  • Cherezov, V., et al.: Science, 318, 1258 (2007),
  • Furse, K., et al.: J. Med. Chem., 46, 4450 (2003),
  • [1]. Yasuda G, et al. The beta 1- and beta 2-adrenoceptor subtypes in cultured rat inner medullary collecting duct cells. Am J Physiol. 1996 Sep;271(3 Pt

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adrenergic Receptor  (肾上腺素能受体)

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