4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)-6-Methoxy-2-Methylpyrimidin-5-Amine 4-氯-N-(4,5-二氢-1H-咪唑-2-基)-6-甲氧基-2-甲基嘧啶-5-胺

CAS 75438-57-2 MFCD75438572

化学结构图

75438-57-2
SMILES: CC1N=C(Cl)C(NC2NCCN=2)=C(N=1)OC

化学属性

Mol. Weight241.68
Mol. FormulaC9H12ClN5O

别名和识别编码

CAS Number75438-57-2
Chemical Name4-Chloro-N-(4,5-Dihydro-1H-Imidazol-2-Yl)-6-Methoxy-2-Methylpyrimidin-5-Amine
Synonym 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine 2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline Lomox Moxon Norcynt Normoxocin Nucynt Physiotens
Chemical Name Translation4-氯-N-(4,5-二氢-1H-咪唑-2-基)-6-甲氧基-2-甲基嘧啶-5-胺
MDL Number
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Moxonidine is an antihypertensive agent.

相关文献及参考

  • [2]. Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate the hypotensive responses of moxonidine but not clonidine. Neuroscience, 2005. 132(4): p. 991-1007.
  • Nasr, M., et al.: Vas. Pharmacol., 53, 53 (2010),
  • Rayment, S., et al.: Brit. J. Pharmacol., 160, 1727 (2010),
  • Taksande, B., et al.: Eur. J. Pharmacol., 637, 89 (2010),
  • [1]. Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.
  • [1]. Schafer, U., et al., Presynaptic effects of moxonidine in isolated buffer perfused rat hearts: role of imidazoline-1 receptors and alpha2-adrenoceptors. J Pharmacol Exp Ther, 2002. 303(3): p. 1163-70.
  • [2]. Chan, C.K., et al., Imidazoline receptors associated with noradrenergic terminals in the rostral ventrolateral medulla mediate th

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Imidazoline Receptor  (咪唑啉受体)

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