(S)-H-1152 (hydrochloride)
CAS 871543-07-6 MFCD71543076
化学结构图
SMILES: CC1=CN=CC2C=CC=C(C1=2)S(=O)(=O)N1CCCNC[C@@H]1C
化学属性
| Mol. Weight | 392.344 |
|---|---|
| Mol. Formula | C16H23Cl2N3O2S |
别名和识别编码
| CAS Number | 871543-07-6 |
|---|---|
| Chemical Name | (S)-H-1152 (hydrochloride) |
| Synonym | 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline |
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分类
- Inhibitors; Protein Kinase Inhibitors and Activators
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
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相关文献及参考
- [2]. Ikenoya M, et al. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002 Apr;81(1):9-16.
- [3]. Lie M, et al. Accelerated neurite growth from spiral ganglion neurons exposed to the Rho kinase inhibitor H-1152. Neuroscience. 2010 Aug 25;169(2):855-62.
- Ikenoya, M., et al.: J. Neurochem., 81, 9 (2002),
- [1]. Tamura M, et al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):245-52. Epub 2005 Sep 12.
- [1]. Tamura M, et al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):245-52. Epub 2005 Sep 12.
- [2]. Ikenoya M, et al. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152,
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