• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Chemical Synthesis, Protecting and Derivatizing Reagents, Protection and Derivatization, Silicon-Based, Synthetic Reagents
• {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment

产品应用

• 用于通过手性硅基炔丙醇的原酸酯 Claisen 重排反应合成对映体富集的联烯硅烷。

相关文献及参考

• Short: III/35D2
• Silylating agent (see Appendix 4): J. Chromat., 147, 291 (1978). Dimethylphenylsilyl (DMPS) ethers are somewhat more resistant to hydrolysis than TMS and are useful in the chromatographic analysis of monosaccharides with UV detection: J. Chromat., 264, 99 (1983); Carbohydr. Res., 119, 241 (1983). See also Dimethyl­phenyl­silane, L04558. The lithio-derivatives of esters and lactones are silylated by DMPSCl on carbon (TMSCl gives O-silylation): J. Am. Chem. Soc., 103, 2418 (1981).
• See also: J. Chem. Soc., Perkin 1, 1209 (1998).
• The reactions of various metallated DMPS derivatives have been extensively studied by Fleming's group and others. DMPSLi gives an organocopper species with CuI which undergoes conjugate addition to enones, to give ß-silyl ketones: J. Chem. Soc., Perkin 1., 2520 (1981):
• For a study of diastereoselectivity in the preparation of ß-silyl esters from ɑß-unsaturated esters and amides attached to chiral auxiliaries, see: J. Chem. Soc., Perkin 1, 303 (1995). For a brief feature on Phenyldimethylsilyllithium, see: Synlett, 1522 (2000).
• Aryl-, alkenyl- and alkynyldimethylchlorosilanes undergo homo-coupling in the presence of TBAF and a catalytic amount of CuI to give biaryls or the corresponding symmetrical dienes or diynes in high yield: J. Chem. Soc., Perkin 1, 797 (1997).
• Short: III/35F
• The DMPS group attached to carbon may function as a masked OH group. Protodesilylation gives the silyl fluoride, which can be converted to the alcohol with overall retention of configuration by reaction with m-CPBA, peracetic acid/ Br2, or peracetic acid/ Mg(OAc)2 with or without Pd(II) catalysis. For a detailed study, see: J. Chem. Soc., Perkin 1, 317 (1995):

安全信息

GHS Symbol

其他信息

• 存储注意事项:氮气保护;湿度敏感
• 检测方法:GC
• 上游原料:乙醚 --> 四氢呋喃 --> 石油醚 --> 甲苯 --> 正己烷 --> 氮 --> 镁 --> 三苯基膦 --> 碘 --> 溴苯 --> 苯甲酰氯 --> 氰化亚铜 --> 锂 --> 二氯二甲基硅烷 --> 二(氰基苯)二氯化钯 --> (N.N-二乙基)氨基二甲基氯硅烷
• Alfa Aesar:二甲基苯基氯硅烷,97+% Chlorodimethylphenylsilane, 97+%(768-33-2)
• Acros Organics:苯基二甲基氯硅烷 Chlorodimethylphenylsilane, 95%(768-33-2)
• TCI Shanghai:二甲基苯基氯硅烷 Chlorodimethylphenylsilane,>;95.0%(GC)(768-33-2)
• F:10-21
• 图谱信息:苯基二甲基氯硅烷(768-33-2)质谱(MS) 苯基二甲基氯硅烷(768-33-2)核磁图( 13 CNMR) 苯基二甲基氯硅烷(768-33-2)核磁图( 1 HNMR)
• Sigma Aldrich:768-33-2(sigmaaldrich)
• 敏感性:Moisture Sensitive
• 苯基二甲基氯硅烷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D1147 二甲基苯基氯硅烷 Chlorodimethylphenylsilane 25ML 773元 2010/06/21 151070250 苯基二甲基氯硅烷 Chlorodimethylphenylsilane 95% 25 GR 1096元 2010/06/21 151070050 苯基二甲基氯硅烷 Chlorodimethylphenylsilane 95% 5 GR 339元
• MOL 文件:768-33-2.mol
• TSCA:Yes