alpha-2-Chloroisodurene 2,4,6-三甲基苄氯

CAS 1585-16-6 MFCD00000901

化学结构图

1585-16-6
SMILES: Cc1cc(C)c(CCl)c(C)c1

化学属性

Mol. FormulaC10H13Cl
Mol. Weight169
Melting Point36.0 to 42.0 deg-C
Flash Point106°(222°F)
TSCANo
Boiling Point119°C/15mmHg(lit.)

别名和识别编码

Chemical Namealpha-2-Chloroisodurene
CAS Number1585-16-6
Alfabeta NameCHLOROMETHYLTRIMETHYLBENZENE 2135()---,,
MDL NumberMFCD00000901
Synonym chloromethylmesitylene 2-Chloromethyl-1,3,5-trimethyl-benzene α-2-Chloroisodurene 2,4,6-Trimethylbenzyl chloride A(2)-Chlorisodurol 2,4,6-三甲基氯苄 Alpha2-chloroisodurene alpha(2)-Chloroisodurene Benzene, 2-(chloromethyl)-1,3,5-trimethyl- α(2)-Chloroisodurene 2-(chloromethyl)-1,3,5-trimethylbenzene 2,4,6-trimethyl-benzyl chloride 2,4,6-三甲基苯甲基氯 α(2)-Chlorisodurol 2,4,6-Trimethylbenzylchlorid ω(2)-Chlor-1,2,3,5-tetramethylbenzol 1-chloromethyl-2,4,6-trimethylbenzene ?2-Chloroisodurene
PubChem Substance ID74108
EC Number216-440-3
Beilstein Registry Number386678
Reaxys-RN386678
Chemical Name Translation2,4,6-三甲基苄氯
InChIKeyUNRGEIXQCZHICP-UHFFFAOYSA-N
LabNetwork Molecule IDLN00140934
InChIInChI=1S/C10H13Cl/c1-7-4-8(2)10(6-11)9(3)5-7/h4-5H,6H2,1-3H3
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分类

  • Aromatics
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Aryl, Building Blocks, C9 to C12, Chemical Synthesis, Halogenated Hydrocarbons, Organic Building Blocks

相关文献及参考

  • Also reported for the protection of thiols (cysteine), stable to refluxing TFA, unlike 4-methoxybenzyl, but cleavable with HF or TfOH-TFA: Coll. Czech. Chem. Commun., 46, 286 (1981), or Ag(I): Chem. Pharm. Bull., 38, 1551 (1990).
  • Short: III/31a
  • Short: III/20b
  • Carboxyl groups can be protected as their 2,4,6-trimethylbenzyl esters by reaction in DMF in the presence of triethylamine. The group can be cleaved by acidolysis (TFA or HBr in AcOH) or hydrogenolysis: Aust. J. Chem., 21, 2831 (1968).

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P234 Keep only in original container. 只保留在原来的容器中。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331
  • P301+P330+P331+P310
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P390 Absorb spillage to prevent material damage. 吸收溢出物,防止重大损害。
  • P405 Store locked up. 上锁保管。
  • P406 Store in corrosive resistant/… container with a resistant inner liner. 存放在耐腐蚀/具有耐性的内衬容器。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Hazard statements
  • H290 May be corrosive to metals 可能腐蚀金属。
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
Packing GroupII
UN Number UN3261 3261
Risk Statements
  • R34 Causes burns 会导致灼伤
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
Hazard Codes C
Storage condition 0-10 0-10°C
Hazard Class8

系列性分类


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