Anthrarufin 蒽绛酚

CAS 117-12-4 MFCD00001210

化学结构图

117-12-4
SMILES: O=C1c2cccc(O)c2C(=O)c2cccc(O)c21

化学属性

Mol. FormulaC14H8O4
Mol. Weight240.21
Melting Point279°C
TSCAYes
Vapor Density8.3 (vs air)
Appearance 1,5-二羟基蒽醌(117-12-4)为从乙酸中析出浅黄色片状结晶。熔点280℃。在120℃可升华。溶于苯和硝基苯,微溶于乙醇;乙酸和乙醚,溶于氢氧化钾溶液呈红色,不溶于碳酸钠溶液和氨水,溶于浓硫酸呈带萤光的红色。
Boiling Point342.92 °C at 760 mmHg

别名和识别编码

Chemical NameAnthrarufin
CAS Number117-12-4
Synonym 1,5-Dihydroxyanthracene-9,10-dione {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-dione {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,5-Dihydroxyanthracene-9,10-
PubChem Substance ID8328
EC Number204-175-6
Beilstein Registry Number1881718
MDL NumberMFCD00001210
Reaxys-RN1881718
Merck Number689
Chemical Name Translation蒽绛酚
Wiswesser Line NotationL C666 BV IVJ DQ KQ
LabNetwork Molecule IDLN00347167
InChIInChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6,15-16H
Canonical SMILESO=C1C2=C(C(O)=CC=C2)C(C3=CC=CC(O)=C13)=O
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分类

  • Alcohols, Materials Science, Monomers, Polymer Science
  • {SNA} Alcohols, Monomers, Polymer Science, 材料科学
  • {uni_hamburg} no charge; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; 14ring; ketone; alcohol; 1fragment
  • {SNA} Alcohols, Materials Science, Monomers, Polymer Science

产品应用

  • An anthraquinone derivative with suppressive effects against nitric oxide (NO) synthase. Potential antimalarial agent. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 protei

相关文献及参考

  • Lee, H. et al.: J. Kor. Soc. App. Biolog. Chem., 53, 831 (2010); Winter, R.W. et al.: Bioorg. Med. Chem. Lett., 5, 1927 (1995); Brinkworth, R.I. et al.: Biochim. Biophys. Acta, Prot. Struct. Mol. Enzy
  • Merck 14 ,689
  • Beil. 8 ,IV,3268
  • RegBook 1 (2), 1689:G / Sax 6 , 1064 / Structure Index 1 , 268:B:3
  • Short: II/3 Title: Luminescence of Organic Substances Author: Schmillen, A.; Legler, R. Editor: Hellwege, K.-H.; Hellwege, A.M. Source: Landolt-Börnstein, New Series Volume: II/3 Year: 1967 ISBN: 3-540-03895-7 ISBN: 978-3-540-03895-5 Internet Resource: DOI:10.1007/b86158 RefComment: 270 figs., VIII, 416 pages. Hardcover Abstract: For more than 1000 luminescent organic substances the most important data are represented as wave numbers of absorption and emission bands, decay times and quantum efficiencies. Additional tables contain further information for restricted groups of substances (figures on typical spectra, wave numbers of sharp single bands, influence of surrounding molecules, etc.).
  • Short: III/35D2 Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Carbon-13, Part 2: Aromatic Compounds Author: Mikhova, B. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35D2 Year: 2005 Keyword: aromatic compounds; carbon-13; chemical shift; coupling constant; molecular structure ISBN: 978-3-540-20189-2 ISBN: 3-540-20189-0 Internet Resource: DOI:10.1007/b83345 RefComment: VIII, 291 p., Hardcover RefComment: Written for Science and engineers in the fields of physics, chemistry and physical chemistry who inted to use NMR to study the structure and the binding of molecules Abstract: Nuclear Magnetic Resonance (NMR) is based on the fact that certain nuclei exhibit a magnetic moment, orient by a magnetic field, and absorb characteristic frequencies in the radiofrequency part of the spectrum. The spectral lines of the nuclei are highly in

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H320 Causes eye irritation 刺激眼睛
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
RTECSCB6630000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,203,1976

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • 图谱信息:1,5-二羟基蒽醌(117-12-4)核磁图( 1 HNMR) 1,5-二羟基蒽醌(117-12-4)红外图谱(IR1) 1,5-二羟基蒽醌(117-12-4)红外图谱(IR2) 1,5-二羟基蒽醌(117-12-4)质谱(MS)
  • 用途二:1,5-二羟基蒽醌是分散染料及酸性染料的中间体。由1,5-二羟基蒽醌磺化可得1,5-二羟基蒽醌-2,6-二磺酸,将这个中间体继续硝化、还原、加成转位、脱磺,可得分散蓝S-BGL。
  • Sigma Aldrich:117-12-4(sigmaaldrich)
  • 用途一:用于合成染料
  • Alfa Aesar:1,5-二羟基蒽醌,tech.90% 1,5-Dihydroxyanthraquinone, tech. 90%(117-12-4)
  • 蒸气密度:8.3 (vs air)
  • MOL 文件:117-12-4.mol
  • 1,5-二羟基蒽醌价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0562 蒽绛酚 Anthrarufin 500G 1700元 2014/06/02 D0562 蒽绛酚 Anthrarufin 25G 234元 2010/05/25 L00848 1,5-二羟基蒽醌, tech. 90% 1,5-Dihydroxyanthraquinone, tech. 90% 10g 239元
  • TCI Shanghai:1,5-二羟基蒽醌 Anthrarufin,>;85.0%(LC)(117-12-4)
  • 上游原料:三氯化铝 --> 蒽 --> 硫酸汞
  • 下游产品:分散兰BGL --> 酸蓝45
  • 方法一:有蒽醌磺化法和苯甲酸磺化法。(1)以蒽醌为原料,以硫酸汞为定位剂,经磺化得到1,5-蒽醌二磺酸和1,8-蒽醌二磺酸。1,5-蒽醌二磺酸经碱熔、酸化即得1,5-二羟基蒽醌。(2)以苯甲酸为原料,经磺化、碱熔、酸化、缩合、闭环而得。此法不用汞催化剂,去除了汞害,但闭环一步收率只有40%,而且耗用大量三氯化铝。该法消耗较高,也带来其他方面的污染,而且生产成本高。

系列性分类


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