2-Chloroethyl Isocyanate 2-氯乙基异氰酸酯

CAS 1943-83-5 MFCD00002043

化学结构图

1943-83-5
SMILES: O=C=NCCCl

化学属性

Mol. FormulaC3H4ClNO
Mol. Weight106
Density1.237
Refractive index1.4440 to 1.4480
Flash Point56°C(lit.)
TSCAYes
Boiling Point141-142
Solubility起反应
Stability对湿度敏感
Appearance 氯乙基异氰酸酯(1943-83-5)为无色液体。沸点 135℃,相对密度 1.237,折光率 1.4490,闪点 56℃,有腐蚀性,可能有致癌作用。

别名和识别编码

Chemical Name2-Chloroethyl Isocyanate
Synonym (2-Chloroethyl)-isocyanat (2-氯乙基)异氰酸酯 -chloro-2-isocyanato-ethan 1-CHLORO-2-ISOCYANATO-ETHANE 1-chloro-2-isocyanato-ethan 1-chloro-2-isocyanato-ethane 1-chloro-2-isocyanatoethane 2-CHLOROETHYL ISOCYANATE 2-CHLOROETHYL ISOCYANATE, LOW HCL, 97% 2-Chlorethylisocyanat 2-Chlorethylisokyanat 2-Chloroethyl isocyanate 2-Chloroethyl isocyanate 97% 2-chlorethylisokyanat 2-chloro-ethyl isocyanate 2-chloroethyl isocyanate 2-氯乙基异氰酯 2-氯乙基异氰酸酯 2-氯代乙基碳酰胺 2-氯异氰酸乙酯 CHLOROETHYLISOCYANATE CIC Ethane, 1-chloro-2-isocyanato- ISOCYANIC ACID 2-CHLOROETHYL ESTER Isocyanic acid, 2-chloroethyl ester Isocyansäure-2-chlor-ethylester {PubCh
MDL NumberMFCD00002043
CAS Number1943-83-5
EC Number217-734-4
Beilstein Registry Number1071429
PubChem Substance ID16035
Alfabeta NameCHLOROETHYLISOCYANATE 2-
Chemical Name Translation2-氯乙基异氰酸酯
Reaxys-RN1071429
Wiswesser Line NotationOCN2G
InChIKeyBCMYXYHEMGPZJN-UHFFFAOYSA-N
LabNetwork Molecule IDLN00008229
InChIInChI=1S/C3H4ClNO/c4-1-2-5-3-6/h1-2H2
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Isocyanates, Nitrogen Compounds, Organic Building Blocks
  • {uni_hamburg} no charge; isocyanate; 1fragment

相关文献及参考

  • Short: EINECS
  • Short: IV/6
  • Beilstein:4(3)245

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S38 In case of insufficient ventilation wear suitable respiratory equipment 通风不良时,佩带适当的呼吸器;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
Risk Statements
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P233 Keep container tightly closed. ?保持容器密闭。
  • P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
  • P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
  • P242 Use only non-sparking tools. 只能使用无火花工具。
  • P243 Take precautionary measures against static discharge. 采取预防措施,防止静电放电。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下,戴呼吸防护。
  • P301+P310
  • P301+P316
  • P301+P330+P331
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P303+P361+P353
  • P304+P340
  • P304+P341
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P316
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P342+P311
  • P342+P316
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P403 Store in a well-ventilated place. 储存在通风良好的地方。
  • P403+P233
  • P403+P235
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
RTECSNQ8450000
Packing GroupIII
UN Number UN3080 1993
Storage condition Moisture Sensitive 对湿度敏感,密封保存。 2-8°C 0-10°C 0-10
Hazard statements
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H301 Toxic if swallowed 吞食有毒
  • H301+H331
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H331 Toxic if inhaled 吸入中毒
  • H332 Harmful if inhaled 吸入有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes
Warnings IRRITANT
Hazard Class3/6.1
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 13 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,3379,1978

其他信息

  • 下游产品:利美尼啶 --> 福莫司汀
  • Acros Organics:异氰酸2-氯乙酯 2-Chloroethyl isocyanate, 98%(1943-83-5)
  • 氯乙基异氰酸酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010345 氯乙基异氰酸酯 25ml 400元 2011/04/16 I0293 异氰酸2-氯乙酯 2-Chloroethyl Isocyanate 25G 887元 2010/06/21 221190010 氯乙基异氰酸酯 2-Chloroethyl isocyanate 98% 1 ML 90元
  • 图谱信息:氯乙基异氰酸酯(1943-83-5)核磁图( 13 CNMR) 氯乙基异氰酸酯(1943-83-5)质谱(MS) 氯乙基异氰酸酯(1943-83-5)红外图谱(IR1)
  • Hazard Note:Toxic/Corrosive/Lachrymatory/Sensitizer
  • 和水反应。
  • 用途一:亚硝基脲类抗肿瘤药物的合成。
  • F:10-19
  • Sigma Aldrich:1943-83-5(sigmaaldrich)
  • MOL 文件:1943-83-5.mol
  • Alfa Aesar:2-氯乙基异氰酸酯,97% 2-Chloroethyl isocyanate, 97%(1943-83-5)
  • TCI Shanghai:2-氯乙基异氰酸酯 2-Chloroethyl Isocyanate,>;95.0%(GC)(1943-83-5)
  • MSDS 信息:2-Chloroethyl isocyanate(1943-83-5).msds
  • 敏感性:Lachrymatory

系列性分类