3-Iodo-L-tyrosine 3-碘-L-酪氨酸

CAS 70-78-0 MFCD00002608

化学结构图

70-78-0
SMILES: N[C@@H](Cc1ccc(O)c(I)c1)C(=O)O

化学属性

Mol. FormulaC9H10INO3
Mol. Weight307.09
Density1.944
Melting Point210°C
Stability对光敏感
Solubilitydilute aqueous acid: soluble
Boiling Point391°C at 760 mmHg

别名和识别编码

Chemical Name3-Iodo-L-tyrosine
CAS Number70-78-0
Synonym H-Tyr(3-I)-OH {LY} H-Tyr(3-I)-OH {} {LY} H-Tyr(3-I)-OH {} {} {LY} H-Tyr(3-I)-OH {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-
EC Number200-744-8
Beilstein Registry Number2941266
MDL NumberMFCD00002608
PubChem Substance ID439744
Reaxys-RN2941266
Merck Number5047
Chemical Name Translation3-碘-L-酪氨酸
LabNetwork Molecule IDLN00194297
InChIInChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
Canonical SMILESO=C(O)[C@@H](N)CC1=CC=C(O)C(I)=C1
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase
  • Inhibitors
  • Amino Acids & Derivatives
  • Chiral Reagents
  • {SNA} Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase,

产品应用

  • 酪氨酸羟化酶抑制剂。

相关文献及参考

  • [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;30(2):153-61.
  • Fitzpatrick, P.F., Steady-state kinetic mechanism of rat tyrosine hydroxylase. Biochemistry 30 , 3658-3662, (1991) 摘要
  • Fitzpatrick, P.F., et al.: Biochemistry, 30, 3658 (1991),
  • Harsing, L.G., et al.: Neuroscience, 77, 419 (1997),
  • Merck 14 ,5047
  • Merck: 14,5047 Beilstein: 14,IV,2369
  • [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
  • [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
  • [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;3

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition -20°C {LY} -20°C 0-10 0-10°C 2-8°C 2-8°C 避光储存 {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

  • Acros Organics:3-碘-L-酪氨酸 3-Iodo-L-tyrosine, 97%(70-78-0)
  • TCI Shanghai:3-碘-L-酪氨酸 3-Iodo-L-tyrosine,>;99.0%(T)(70-78-0)
  • 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 515元 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1680元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
  • 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 488元 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1600元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
  • MOL 文件:70-78-0.mol
  • Sigma Aldrich:70-78-0(sigmaaldrich)
  • F:8-10-23
  • 溶于15份沸水。

系列性分类


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