5α-Androstan-17β-ol-3-one 雄诺龙

CAS 521-18-6 MFCD00003667

化学结构图

521-18-6
SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O

化学属性

Mol. FormulaC19H30O2
Mol. Weight290.49
Melting Point173-183 ºC

别名和识别编码

Chemical NameAndrostanolone
CAS Number521-18-6
Synonym {uni_hamburg} 17BETA-HYDROXY-5ALPHA-ANDROSTAN-3-ONE 5α-Androstanolone Anabolex androstanolone (INN) 17-beta-hydroxy-5-alpha-androstan-3-on 5ALPHA-ANDROSTAN-17BETA-OL-3-ONE (5alpha,17beta)-17-Hydroxy-androstan-3-one (5-alpha,17-beta)-17-hydroxyandrostan-3-one 雄烯醇酮 DHT Testosterone, dihydro- 17b-hydroxy-5a-androstan-3-one (5S,8R,10S,13S,17S)-17-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenan 4-Dihydrotestosteron 4,5α-Dihydrotestosterone Androstanolone 17beta-Hydroxy-3-androstanone 5?-Dihydrotestosterone 17-beta-Hydroxy-5-alpha-androstan-3-one 5α-Androstan-17β-ol-3 Androstalone Neodrol Anaboleen 5-ALPHA-ANDROSTANOLONE 5ALPHA-DIHYDROTESTOSTOSTERONE 5ALPHA-DIHYDROTESTOSTERONE Andractim 17β-hydroxy Androstanolone; 4-Dihydrotestosterone; 5a-Dihydrotestosterone; 5a-Androstan-17b-ol-3-one; 17b-Hydroxy-5a-androstan-3-one 4,5α-双氢睾酮 5α,17β-Hydroxyandrostan-3-one 5α- Proteina 加氢睾酮 Androlone 雄诺龙 STANOLONE 17β-Hydroxy-3-androstanone Protona 5A-ANDROSTAN-17B-OL-3-ONE 4,5-alpha-Dihydrote 双氢睾酮(最终用户声明) 5α-二氢睾酮 (5?,17?)-17-Hydroxyandrostan-3-one Stanaprol ANDROSTANOLONE Dihydrotestosterone Cristerona MB 5-alpha-Dihydrotestosterone 5A-DIHYDROTESTOSTERONE (5S,8R,9S,10S,13S,14S,17S)-17-HYDROXY-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN- Stanolone {ha
MDL NumberMFCD00003667
PubChem Substance ID10635
Beilstein Registry Number2056371
EC Number208-307-3
Chemical Name Translation雄诺龙
Merck Number13,8872
Wiswesser Line NotationL E5 B666 OVTJ A1 E1 FQ
LabNetwork Molecule IDLN00838892
InChIInChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
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分类

  • Androgen, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones
  • {uni_hamburg} no charge; carbocycle; alicycle; large ring; fused rings; 5ring; 6ring; 9ring; 10ring; 13ring; 14ring; 17ring; ketone; alcohol; chiral; 1fragment
  • {SNA} A, AM to AQ, AN-AZ, APIs & Metabolites, APIs (Active Pharmaceutical Ingredients) & Metabolites, All Doping Standards (A-Z), All alphabetically sorted, Alphabetical Index of Analytical Standards, Anabolic Steroide, Analytical Standards, Analytical/Chromatography, Application Areas and Market Segments, Bioactive Small Molecules, Boldenone & Metabolites, Cell Biology, Chromatography,

产品应用

  • Anabolic steroid.

相关文献及参考

  • Schneider, M., et al.: J. Biotechnol., 46, 161
  • Merck 14 ,8793
  • Beil. 8 ,IV,634
  • Short: III/35E Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts for Oxygen-17 Author: Duddeck, H.; Toth, G.; Simon, A. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35E Year: 2002 Keyword: Alipathic and Aromatic hydrocarbons; Coupling constant j; Nuclear Magnetic Resonance; chemical shifts δ ISBN: 3-540-42501-2 ISBN: 978-3-540-42501-4 Internet Resource: DOI:10.1007/b92953 RefComment: VII, 230 pages. With CD-ROM., Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1 (subvol. C), carbon-13 (subvol. D), and oxygen-17 (subvol. E) compounds are tabulated together with the gross- and structure formulas and the most readily available solvents. Due to the large amount of the data merely chemical shifts are presented in the printed versions, and all the data, chemical shifts and coupling constants are provided on CD-ROM's.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

RTECSBV8052000
Precautionary statements
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Hazard Codes T Xn
WGK Germany3
GHS Symbol
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Danger
Safety Statements
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
TYPE OF TEST            : Sperm Morphology
ROUTE OF EXPOSURE       : Parenteral
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 12 mg/8W (Intermittent)
REFERENCE :
   JEZOAO Journal of Experimental Zoology.  (Alan R. Liss, Inc., 41 E. 11th
   St., New York, NY 10003) V.1-    1904-  Volume(issue)/page/year:
   205,403,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 160 mg/kg
SEX/DURATION            : female 14-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   94,979,1974

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 700 ug/kg
SEX/DURATION            : female 14 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 5,489,1972

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 17500 ug/kg
SEX/DURATION            : female 35 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   RPHRA6 Recent Progress In Hormone Research.  Proceedings of the Laurentian
   Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
    V.1-    1947-  Volume(issue)/page/year: 20,395,1964

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 24 mg/kg
SEX/DURATION            : female 3 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   FESTAS Fer

其他信息

  • 图谱信息:雄诺龙(521-18-6)核磁图( 13 CNMR) 雄诺龙(521-18-6)红外图谱(IR2) 雄诺龙(521-18-6)红外图谱(IR1)
  • 用途一:雄激素类药。
  • MSDS 信息:4-Dihydrotestosterone(521-18-6).msds
  • 外观性质:白色或类白色结晶性粉末。熔点:173-183 ºC 比旋光度:27
  • 比旋光度:27 °
  • Sigma Aldrich:521-18-6(sigmaaldrich)
  • MOL 文件:521-18-6.mol

系列性分类


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