Benzo[a]phenanthrene, 99%, reference material 屈

CAS 218-01-9 MFCD00003698

化学结构图

218-01-9
SMILES: c1ccc2c(c1)ccc1c3ccccc3ccc21

化学属性

Mol. FormulaC18H12
Mol. Weight228
Boiling Point448
Melting Point252-254
Density0.7915
TSCAYes
Solubility不溶

别名和识别编码

Chemical NameBenzo[a]phenanthrene, 99%, reference material
CAS Number218-01-9
Synonym Chrysene
PubChem Substance ID9171
EC Number205-923-4
Beilstein Registry Number1909297
MDL NumberMFCD00003698
Reaxys-RN1909297
Merck Number2255
Chemical Name Translation
Wiswesser Line NotationL E6 B666J
LabNetwork Molecule IDLN01277834
InChIInChI=1S/C18H12/c1-3-7-15-13(5-1)9-11-18-16-8-4-2-6-14(16)10-12-17(15)18/h1-12H
Canonical SMILESC12=CC=CC=C1C=CC3=C4C=CC=CC4=CC=C23
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分类

  • Alphabetic, Analytical Standards, Analytical/Chromatography, C, CH,
  • {SNA} All PAH Standards, Alpha Sort, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Aromatics, C, CH, Chemical Class, Chromatography, Environmental Standards, Hydrocarbons, Neats and Solutions, PAHs, Standards for Personal Care and Cosmetic Products, Volatiles/ Semivolatiles, neat, neats, prohibited substances (EU-REGULATION No 1223/2009)
  • {SNA} All PAH Standards, Alphabetical Index of Analytical Standards, Ana

产品应用

  • 用于非磁性金属表面探伤用荧光剂、化学仪器紫外线过滤剂、光敏剂及照像感光剂,用于染料生产,代替洗油作农药敌稗的溶剂和增效剂。

相关文献及参考

  • Merck:2255 Beilstein:5,718
  • Short: II/27C
  • Diamond, S., et al.: Environ. Toxicol. Chem., 25, 3015 (2006),
  • Anderson, D., et al.: Mutat. Res., 307, 261 (1994),
  • Fotakis, G., et al.: Toxicol. Lett., 160, 171 (2006),
  • Merck:2255
  • Short: II/27B

安全信息

GHS Symbol
WGK Germany3
Hazard Codes 9
Hazard statements
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H350 May cause cancer 可能致癌
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSGC0700000
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P318
  • P203
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
Signal word Danger
UN Number 3077
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险
  • R45 May cause cancer 可能致癌
  • R50/53
Packing GroupIII
Hazard Class9
Storage condition 2-8°C 室温储存
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3600 ug/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   38,1831,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40 mg/kg/3W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CCSUDL Carcinogenesis--A Comprehensive Survey.  (Raven Press, 1185 Ave. of
   the Americas, New York, NY 10036)  V.1-    1976-  Volume(issue)/page

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 99 mg/kg/31W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   11,301,1951

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   15,632,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 62,911,1979

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Sc

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Administration onto the skin
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 192 umol/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 5,231,1984

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 6 umol/L
REFERENCE :
   DTESD7 52 Vanderbilt Ave., New York, NY 10017)  V.1-15, 1977-87.
   Discontinued 52 Vanderbilt Ave., New York, NY 10017)  V.1-    1977-
   Volume(issue)/page/year: 10,277,1982

TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   19,259,1992

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 5 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 156,61,1985

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - hamster Embryo
DOSE/DURATION           : 10 mg/L
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)

其他信息

  • 多环芳烃(PAHs)单组分标准液
  • 在苯中结成无色斜方片晶,在紫外线下有紫色荧光,可燃,有毒,真空中易升华,微溶于醇、醚、二硫化碳和冰醋酸,在25℃时1g能溶于1300ml无水乙醇、480ml甲苯,在100℃时在甲苯中约溶解5%,略溶于沸苯,不溶于水。

系列性分类


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