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分类

• {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Excitatory Amino Acids, M, NMDA Agonists, Neuroscience, Neurotransmission, Neurotransmitters, 细胞生物学
• {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, M, NMDA Agonists, Neuroscience, Neurotransmission, Neurotransmitters
• {SNA} Excitatory Amino Acids, NMDA Agonists, Neuroscience, Neurotransmission, Neurotransmitters, 细胞信号转导和神经科学, 细胞生物学
• {SNA} Amino Acids,

相关文献及参考

• [2]. Yoneda Y, et al. Enhancement of [3H]glutamate binding by N-methyl-D-aspartic acid in rat adrenal. Brain Res. 1987 Mar 17;406(1-2):24-31.
• [3]. Jiang L, et al. Decrease of growth and differentiation factor 10 contributes to neuropathic pain through N-methyl-D-aspartate receptor activation. Neuroreport. 2017 May 24;28(8):444-450.
• [1]. Xia JD, et al. Centrally mediated ejaculatory response via sympathetic outflow in rats: role of N-methyl-D-aspartic acid receptors in paraventricular nucleus. Andrology. 2016 Nov 16.
• [1]. Xia JD, et al. Centrally mediated ejaculatory response via sympathetic outflow in rats: role of N-methyl-D-aspartic acid receptors in paraventricular nucleus. Andrology. 2016 Nov 16.
• [2]. Yoneda Y, et al. Enhancement of [3H]glutamate binding by N-methyl-D-aspartic acid in rat adrenal. Brain Res. 1987 Mar 17;406(1-2):24-31.
• [3]. Jiang L, et al. Decrease of growth and differentiation factor 10 contributes to neuropathic

安全信息

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 137 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 269,573,1994

其他信息

• N-Methyl-D-Aspartic acid (NMDA) is a synthetic agonist of the NMDA receptor that mimics the binding action of the endogenous ligand glutamate. The NMDA receptor is a voltage-gated ion channel intimately involved in spatial learning and memory, and perturbing the normal behavior of this receptor system with NMDA exposure has facilitated elucidation of NMDA receptor-mediated activities.
• N-甲基-D-天冬氨酸