Ethylene Glycol-Bis(2-Aminoethylether)-N,N,N',N'-Tetraacetic Acid 乙二醇双(2-氨基乙基醚)四乙酸

CAS 67-42-5 MFCD00004291

化学结构图

67-42-5
SMILES: O=C(O)CN(CCOCCOCCN(CC(=O)O)CC(=O)O)CC(=O)O

化学属性

Mol. FormulaC14H24N2O10
Mol. Weight380.35
Density1.433
Melting Point240-245°C
TSCAYes
SolubilitySoluble in 1M NaOH (100 mM), Slightly soluble in water., Soluble in 1M NaOH (100 mM), Slightly soluble in water.
Stability对湿度敏感
Boiling Point678°C at 760 mmHg

别名和识别编码

Chemical NameEthylene Glycol-Bis(2-Aminoethylether)-N,N,N',N'-Tetraacetic Acid
Synonym EGTA {LY} EGTA {} {LY} EGTA {} {} {LY} EGTA {} {} {} {LY} EGTA {} {} {} {} {LY} EGTA {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} EGTA {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {}
CAS Number67-42-5
EC Number200-651-2
Beilstein Registry Number1717370
MDL NumberMFCD00004291
PubChem Substance ID87569411
Merck Number3529
Alfabeta NameBISCARBOXYMETHYLDIOXADIAZATETRADECANEDIOICACIDEGTA 31269312114(())--------,,,,
Reaxys-RN1717370
Chemical Name Translation乙二醇双(2-氨基乙基醚)四乙酸
Wiswesser Line NotationQV1N1VQ2O2O2N1VQ1VQ
LabNetwork Molecule IDLN00182129
Canonical SMILESO=C(O)CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O
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分类

  • {SNA} BioUltra, 分子生物学, 分子生物学试剂, 生化试剂, 螯合剂
  • {SNA} Core Bioreagents, Enzyme Inhibitors, Research Essentials, 生化试剂, 螯合剂
  • {SNA} Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, Biochemicals and Reagents, Chel

产品应用

  • EGTA是最为被广泛使用的钙离子选择性的螯合剂,用于在镁存在下,测定钙。它与钙离子形成的复合物比与镁离子形成的复合物要稳定100,000倍,被用来制备钙缓冲液和控制钙离子的浓度。容量分析及光度分析中测量微量金属的络合剂、掩蔽剂。也可滴定钡、锶、铜、镁和锌。
  • RNA逆转录酶中RNA的脱氧测序缓冲器组分

相关文献及参考

  • Merck: 14,3529
  • Reagent for complexometry.

安全信息

Signal word Warning
GHS Symbol
WGK Germany2
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
RTECSAH3760000
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Warnings IRRITANT
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} { {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3587 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   16,807,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD691-490

其他信息

  • 用途二:EGTA是最为被广泛使用的钙离子选择性的螯合剂。它与钙离子形成的复合物比与镁离子形成的复合物要稳定100,000倍,被用来制备钙缓冲液和控制钙离子的浓度。容量分析及光度分析中测量微量金属的络合剂、掩蔽剂。也可滴定钡、锶、铜、镁和锌。
  • 用途一:是一种钙的鳌合剂,钾盐的效果相对好一些。
  • 外观性质:白色结晶性粉末。溶于碱溶液,几乎不溶于水。熔点:241℃
  • TCI Shanghai:乙二醇双(2-氨基乙基醚)四乙酸 Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid,>;95.0%(T)(67-42-5)
  • MOL 文件:67-42-5.mol
  • Acros Organics:乙二醇双氨乙基醚四乙酸/EGTA Ethylenebis(oxyethylenenitrilo)tetraacetic acid, 97%(67-42-5)
  • 溶于碱溶液,几乎不溶于水。
  • 乙二醇双(2-氨基乙基醚)四乙酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 30085316 乙二醇双(2-氨基乙基)四乙酸 100g 197.7元 2011/04/16 E0805 乙二醇双(2-氨基乙基醚)-N,N,N',N'-四乙酸[用于生化研究] Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid [for Biochemical Research] 25G 1030元 2011/04/16 E0805 乙二醇双(2-氨基乙基醚)-N,N,N',N'-四乙酸[用于生化研究] Ethylene Glycol Bis(2-aminoethyl Ether)-N,N,N',N'-tetraacetic Acid [for Biochemical Research] 5G 343元
  • Sigma Aldrich:67-42-5(sigmaaldrich)
  • Alfa Aesar:乙二醇-O,O'-二(3-氨乙基)-N,N,N',N'-四乙酸,97% Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 97%(67-42-5)
  • MSDS 信息:Ethylenebis(oxyethylenenitrilo)tetraacetic acid(67-42-5).msds
  • 海关编码:29225000

系列性分类