(E)-3-(4-methoxyphenyl)acrylic Acid (E)-3-(4-甲氧苯基)丙烯酸

CAS 943-89-5 MFCD00004398

化学结构图

943-89-5
SMILES: COc1ccc(/C=C/C(=O)O)cc1

化学属性

Mol. FormulaC10H10O3
Mol. Weight178.18
Melting Point173.5 °C
Density1.422
TSCAYes
Appearance 白色结晶体,溶于乙醇,乙酸乙酯等有机溶剂中。熔点170-174℃,含量≥99.0%。
Boiling Point342.6±17.0 °C at 760 mmHg

别名和识别编码

Chemical Name(E)-3-(4-methoxyphenyl)acrylic Acid
Alfabeta NameMETHOXYPHENYLPROPENOICACID E342(())-----
MDL NumberMFCD00004398
CAS Number943-89-5
Synonym (E)-3-(4-Methoxyphenyl)acrylic acid {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (E)-3-(4-Methoxyphenyl)acrylic acid {} {} {} {} {} {} {} {} {}
PubChem Substance ID699414
Beilstein Registry Number2208397
EC Number213-405-4
Reaxys-RN2208397
Chemical Name Translation(E)-3-(4-甲氧苯基)丙烯酸
InChIKeyAFDXODALSZRGIH-QPJJXVBHSA-N
InChIInChI=1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-4+
Canonical SMILESO=C(O)/C=C/C1=CC=C(OC)C=C1
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分类

  • {SNA} Aloe Vera, Building Blocks, C1
  • Aloe Vera, Building Blocks, C10, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Curcuma longa (Turmeric), Liquid Crystals, Materials Science, Nematic, Nutrition Research,

产品应用

  • p-MCA exerted antihyperglycemic/hypoglycemic effect by stimulating insulin secretion from pancreas and could be developed into a new potential for therapeutic agent used in type 2 diabetic patients.

相关文献及参考

  • ########
  • Beilstein:10,298
  • Short: EINECS
  • Short: VIII/5A

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word
RTECSUD3391300
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1300 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   IJSIDW Indian Journal of Pharmaceutical Sciences.  (Kalina, Santa Cruz
   (East), Bombay 400 029, India)  V.40(2)-    1978-  Volume(issue)/page/year:
   49,77,1987

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • Sigma Aldrich:943-89-5(sigmaaldrich)
  • MOL 文件:943-89-5.mol
  • 对甲氧基肉桂酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/05/25 A13870 反-4-甲氧基肉桂酸, 98+% trans-4-Methoxycinnamic acid, 98% 50g 720元 2010/05/25 A13870 反-4-甲氧基肉桂酸, 98+% trans-4-Methoxycinnamic acid, 98% 250g 2884元 2010/05/25 A13870 反-4-甲氧基肉桂酸, 98+% trans-4-Methoxycinnamic acid, 98% 10g 190元
  • MSDS 信息:3-(4-Methoxyphenyl)-2-propenoic acid(830-09-1).msds
  • 制备方法:以对甲氧基苯甲醛为原料,醋酸铵为催化剂,采用微波辐射技术,经鼬溉verta烈反应,在无溶剂条件下合成了对甲氧基肉桂酸。
  • F:8
  • MOL 文件:830-09-1.mol
  • Hazard Note:Irritant
  • Acros Organics:4-甲氧基肉桂酸 p-Methoxycinnamic acid, predominantly trans, 99%(830-09-1)
  • TCI Shanghai:4-甲氧基肉桂酸 4-Methoxycinnamic Acid,>;98.0%(T)(830-09-1)
  • 4-甲氧基肉桂酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0576 4-甲氧基肉桂酸 4-Methoxycinnamic Acid 25G 412元 2010/06/21 125840250 4-甲氧基肉桂酸 p-Methoxycinnamic acid 99%, predominantly trans 25 GR 486元 2010/06/21 125841000 4-甲氧基肉桂酸 p-Methoxycinnamic acid 99%, predominantly trans 100 GR 1492元
  • Alfa Aesar:反-4-甲氧基肉桂酸,98+% trans-4-Methoxycinnamic acid, 98%(943-89-5)
  • 检测方法:HPLC,NMR
  • 对甲氧基肉桂酸类防晒剂:目前最常用的对甲氧基肉桂酸类防晒剂为对甲氧基肉桂酸辛酯,为无色或淡黄色液体,不溶于水,溶于乙醇、乙酸乙酯等有机溶剂中,对皮肤无刺激性,使用安全性高,而且对于UVB区紫外线吸收率高,能有效防止280-330mm的紫外线,且吸收率高,是一种防护UVB紫外线完美的防晒剂;能够有效的防止皮肤晒红、晒伤;目前在各个国家的许多防晒类化妆品中都广泛的使用这个原料。由对甲氧基苯甲醛与丙二酸反应而得。
  • 用途一:主要用于化妆品紫外线吸收
  • Sigma Aldrich:830-09-1(sigmaaldrich)

系列性分类


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