Spiro[isobenzofuran-​1(3H)​,​9'-​[9H]​xanthen]​-​3-​one, 6-​amino-​3',​6'-​dihydroxy- 6-氨基荧光素

CAS 51649-83-3 MFCD00005051

化学结构图

51649-83-3
SMILES: NC1C=C2C(=CC=1)C(=O)OC12C2C=CC(O)=CC=2OC2C=C(O)C=CC1=2

化学属性

Mol. FormulaC20H13NO5
Mol. Weight347
Melting Point285

别名和识别编码

Chemical NameSpiro[isobenzofuran-​1(3H)​,​9'-​[9H]​xanthen]​-​3-​one, 6-​amino-​3',​6'-​dihydroxy-
CAS Number51649-83-3
Synonym Fluoresceinamine isomer II
PubChem Substance ID87562378
EC Number257-334-7
Beilstein Registry Number51708
MDL NumberMFCD00005051
Reaxys-RN51708
Chemical Name Translation6-氨基荧光素
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分类

  • {SNA} Alphabetical, Biochemicals and Reagents, Carbohydrate Labels,
  • {SNA} Derivatization agents, Functional Group Reactive Labels, Functional Group Reactive Labels for Immunoassays, 发光化合物及其检测, 生化试剂, 荧光探针,标记,粒子和染色剂
  • Alphabetical, Biochemicals and Reagents, Carbohydrate Labels, Carbohydrate Labels for Chromatograp

产品应用

  • Fluorescent labeling reagent for proteins. Used in the fluorescent antibody technique for rapid identification of pathogens.

相关文献及参考

  • Riggs, H.J.L., et al.: Amer. J. Pathol., 34, 1081 (1958),
  • Mann, K.G. and Fish, W.W., Methods in Enz., 26, 28 (1972),
  • 1. Partha, R., Lackey, M., Hirsch, A., et al., Self assembly of amphiphilic C60 fullerene derivatives into nanoscale supramolecular structures J. Nanobiotechnology 5 , 1, (2007) 摘要
  • 2. Daneshvar, B., Frandsen, H., Autrup, H., et al., γ-Glutamyl semialdehyde and 2-amino-adipic semialdehyde: biomarkers of oxidative damage to proteins Biomarkers 2 , 117, (1997)
  • Beil. 19 ,V,8,713
  • FT-IR 1 (2), 1013:C / FT-IR 2 (3), 4152:C / IR-Spectra (3), 1475:A / RegBook 1 (2), 2797:H / Sigma FT-IR 1 (2), 147:C / Stains and Dyes Ref , 381 / Structure Index 1 , 445:B:4

安全信息

GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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