(S)-(+)-2-Pyrrolidinemethanol (S)-(+)-2-吡咯烷甲醇

CAS 23356-96-9 MFCD00005255

化学结构图

23356-96-9
SMILES: OC[C@@H]1CCCN1

化学属性

Mol. FormulaC5H11NO
Mol. Weight101
Refractive index1.4840 to 1.4880
Boiling Point74-76
Density1.025
Flash Point86°C(lit.)
TSCANo
Melting Point42-44°
Stability对空气敏感

别名和识别编码

Chemical Name(S)-(+)-2-Pyrrolidinemethanol
CAS Number23356-96-9
Alfabeta NamePYRROLIDINYLMETHANOL S2()---
MDL NumberMFCD00005255
Synonym (S)-(+)-2-(Hydroxymethyl)pyrrolidine, (S)-(+)-2-Pyrrolidinemethanol (S)-(+)-2-(Hydroxymethyl)pyrrolidine; (S)-(+)-2-Pyrrolidinemethanol (S)-(+)-2-(羟甲基)吡咯烷 (S)-(+)-2-吡咯烷甲醇 H-Pro-ol
PubChem Substance ID87575194
EC Number245-605-2
Beilstein Registry Number79843
Reaxys-RN79843
Chemical Name Translation(S)-(+)-2-吡咯烷甲醇
InChIKeyHVVNJUAVDAZWCB-UHFFFAOYSA-N
LabNetwork Molecule IDLN00008403
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Intermediates
  • {SA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Pyrrolidines
  • Heterocycles
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Heterocyclic Building Blocks, Pyrrolidines

产品应用

  • rac-Prolinol is an intermediate in the synthesis of Physostigmine and Physostigmine derivative used for treatment of Alzheimer's disease.

相关文献及参考

  • Pei-Pei, K., et al.: J. Med. Chem., 42, 4705 (1999),
  • Beilstein: 21,V,1,77
  • Siucak, J., et al.: Neuropharmacol., 51, 386 (2006),

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard Codes Xi
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H227 Combustible liquid 可燃液体
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P235
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S37 Wear suitable gloves 戴适当手套;
Storage condition Air Sensitive & Hygroscopic

系列性分类


相关产品推荐