Imidazo[1,2-a]Pyridine 咪唑并[1,2-a]吡啶

CAS 274-76-0 MFCD00005553

化学结构图

274-76-0
SMILES: c1ccn2ccnc2c1

化学属性

Mol. FormulaC7H6N2
Mol. Weight118
Boiling Point98°C/3mmHg(lit.)
Density1.165 g/mL at 25 °C(lit.)
Refractive index1.6230 to 1.6270
Flash Point113 ºC

别名和识别编码

Chemical NameImidazo[1,2-a]Pyridine
CAS Number274-76-0
Alfabeta NameIMIDAZOPYRIDINE A12[]-,
MDL NumberMFCD00005553
Synonym 1,3a-Diazaindene 1-Azaindolizine 1-azaindolizine 1-azainolizine Imidazo[1,2-a]pyridine Pyridino[1',2':1,2]glyoxaline Pyrimidazole imidazo(1,2-a)pyridine {} {uni_hamburg} 咪唑并[1,2-a]吡啶
PubChem Substance ID78960
Chemical Name Translation咪唑并[1,2-a]吡啶
LabNetwork Molecule IDLN00167503
Reaxys-RN109466
InChIInChI=1S/C7H6N2/c1-2-5-9-6-4-8-7(9)3-1/h1-6H
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分类

  • Intermediates
  • Aromatics
  • Heterocycles
  • {SNA} Building Blocks, C7, Chemical Synthesis, Heterocyclic Building Blocks, Imidazopyridines, Pyridines
  • {uni_hamburg} no charge; nitrogen heterocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; 1fragment

产品应用

  • Imidazo[1,2-a]pyridine is one of four imidazopyridine isomers. Imidazopyridine derivatives possess activity as inhibitors of target enzymes and have medicinal and pharmaceutical applications and are u

相关文献及参考

  • Liu, J. et al.: Huax. Jinz., 22, 631 (2010);
  • Short: III/35B Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Fluorine-19 and Nitrogen-15 Author: Balasubramanian, M.; Gupta, R.R.; Jain, M.; Perumal, S. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35B Year: 1998 ISBN: 3-540-63275-1 ISBN: 978-3-540-63275-7 Internet Resource: DOI:10.1007/b55685 RefComment: VII, 242 pages. With CD-ROM. Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1 (subvol. C), and carbon-13 (subvol. D) compounds are tabulated together with the gross- and structure formulas and the most readily available solvents. Due to the large amount of the data merely chemical shifts are presented in the printed versions, and all the data, chemical shifts and coupling constants are provided on CO-ROM's.

安全信息

Warnings IRRITANT
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
GHS Symbol
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes Xi
Safety Statements
  • S37/39 Wear suitable gloves and eye/face protection 穿戴适当的手套和眼睛/面保护;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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