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• 试剂商城
• 直接询价

分类

• {Chemicalbook} 农药中间体: 杀菌剂中间体: 酰胺类杀菌剂
• {SA} Building Blocks, Carbonyl Compounds, Carboxylic Acid Anhydrides, Chemical Synthesis, Organic Building Blocks
• {uni_hamburg} no charge; oxygen heterocycle; carbocycle; aromatic; large ring; fused rings; 5ring; 6ring; 9ring; carbo-anhydride; 1fragment
• {SNA} ACS Grade, Building Blocks, Carbonyl Compounds, Carboxylic Acid Anhydrides, Chemical Synthesis, Essential Chemicals, Inorganic Salts, Solutions and Reagents, Organic Building Blocks, Research Essentials

产品应用

• 标定碱的标准溶液，从仲醇、叔醇中分离伯醇。根据形成衍生物的溶点不同，检别伯胺和芳香族烃。除去苯中噻吩。

相关文献及参考

• Short: II/27B
• Can be used for the dehydration of nitro aldols to nitroalkenes; see, e.g.: Org. Synth. Coll., 7, 396 (1990).
• Reaction with H2O2 gives monoperphthalic acid, useful in peroxidation reactions; see, e.g.: Org. Synth. Coll., 3, 619 (1955); 5, 805 (1973). With urea hydrogen peroxide, provides a superior system for converting N-heteroaromatics and tert-amines to their N-oxides: Chem. Ber., 125, 1965 (1992)
• Merck: 14,7372
• For examples of formation of phthalimides from amines, see: Org. Synth. Coll., 4, 106 (1963); 5, 973 (1973). As an alternative to hydrazinolysis, ɑ-amino acids can also be quantitatively recovered from their phthaloyl derivatives by prolonged reaction with aqueous methylamine at room temperature: Can. J. Chem., 48, 3572 (1970).
• Short: III/20a
• Merck: 14,7372 Beilstein:17,469

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   29ZWAE "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH,
   Chemical Rubber Co., 1968  Volume(issue)/page/year: -,410,1968

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >210 mg/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810
   Frontage Rd., Northbrook, IL 60062)  Volume(issue)/page/year: 13-4/1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets.  (1810
   Frontage Rd., Northbrook, IL 60062)  Volume(issue)/page/year: 13-4/1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1530 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology,
   Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128)  V.1-
   1990-  Volume(issue)/page/year: 15(Suppl 1),S68,1996

TYPE OF TEST            : LD50 - Lethal d

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 3 mmol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   24,181,1994

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 203 mg/kg
SEX/DURATION            : female 8-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis.  (Alan R. Liss, Inc.,
   41 E. 11th St., New York, NY 10003)  V.1-    1980- Volume(issue)/page/year:
   2,61,1982

TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 mg/m3
SEX/DURATION            : male 45 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 35(1),105,1970

其他信息

• 苯酐价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 10015618 邻苯二甲酸酐;苯二甲酸酐;苯酐;1,2-苯二甲酸酐;1,3-异苯并呋喃二酮;酞酸酐;酞酐 500g 25元 2011/08/23 10015628 邻苯二甲酸酐;苯二甲酸酐;苯酐;1,2-苯二甲酸酐;1,3-异苯并呋喃二酮;酞酸酐;酞酐 500g 24元 2011/08/23 xp400329 邻苯二甲酸酐;苯二甲酸酐;苯酐;1,2-苯二甲酸酐;1,3-异苯并呋喃二酮;酞酸酐;酞酐 5g 37元
• {Chemicalbo
• 用途一:用作分析试剂，也用于有机合成
• 急性毒性:口服- 大鼠 LD50:4020 毫克/ 公斤; 口服- 小鼠
• 用途三:邻苯二甲酸酐简称苯酐，是杀菌剂灭菌丹、杀虫剂亚胺硫磷、除草剂灭草松的中间体。
• 方法二:目前在工业生产中有两种苯酐原料路线，即邻二甲苯法(简称邻法)和萘法。生产工艺有三种：固定床氧化法、流化床气相氧化法和液相法。世界苯酐生产中以邻法固定床氧化技术为主，大约占苯酐生产总能力的80%以上。1.邻二甲苯氧化法一般采用以五氧化二钒为主的钒系催化剂进行邻二甲苯的气相氧化，反应器多数为列管式固定床。将过滤后的无尘气经压缩、预热，与气化的邻二甲苯蒸气混合后进入反应器，在400-460℃进行氧化反应，进料空速2000-3000h-1，空气中邻二甲苯浓度40-60g/m2（标准），反应热由管外循环的熔盐带出。反应产物进入蒸气生器，被冷却的反应气经进一步冷却，回收粗苯酐。尾气经水洗回收顺丁烯二酸酐后放空。粗苯酐经减压粗馏，由塔丁分离出低沸点的顺丁烯二酸酐，甲基顺丁烯二酸酐及苯甲酸等；塔底物料经真空精馏，得到苯酐产品。原料消耗定额：邻二甲苯（98%）1138kg/t。2.萘催化氧化法萘熔融气化后与空气在沸腾床或固定床反应器内，在催化剂五氧化二钒存在下，催化氧化生成苯酐气体，经冷凝热熔而得粗酐，通过热处理后再经减压蒸馏、冷凝、分离而得精苯酐。原料消耗定额：萘（95%以上）11250kg/t。
• 刺激数据:皮肤- 兔子 500 毫克/
• MOL 文件:85-44-9.mol
• {Chemical
• 毒性分级:中毒
• 蒸气密度:5.1 (vs air)
• 下游产品:2,3,4,5-四氟苯甲酸 --> 2-甲基蒽醌 --> 2-苯乙基苯甲酸 --> 邻苯甲酰苯甲酸 --> 2,2-二苯基-1-苦味基肼自由基 --> 1,2,5-氧恶唑-3-羧酸 --> 环辛烯 --> 荧光素 --> 邻苯二甲酸二正辛酯(DNOP) --> 3-甲基-1,2,5-噁二唑 --> 氨基树脂清漆 --> 吲哚布芬 --> 灭菌丹 --> 邻苯二甲酸二癸酯 --> 邻苯二甲酸二烯丙酯 --> 醇酸绝缘漆 --> N-羟甲基邻苯二甲酰亚胺 --> 邻苯二甲酸单吗啉 --> N-(2-溴乙基)邻苯二甲酰亚胺 --> 酞酸二异癸酯 --> 邻苯二甲酸二异丁酯 --> 2-乙基蒽醌 --> 2-氯蒽醌 --> 2-(3'-氯磺酰基-4'-氯苯甲酰)苯甲酸 --> 邻苯二甲酸二戊酯 --> 邻苯二甲酸二环己酯 --> 亚苄基酞 --> 溶剂橙 60 --> N-苯基邻苯二甲酰亚胺 --> 邻苯二甲酸二异壬酯 --> 邻苯二甲酸氢钾 --> 2-(四氢-2,6-二氧代吡喃-3-基)异吲哚-1,3(2H)二酮 --
• 用途四:苯酐是最重要的有机化工原料之一，其主要衍生物有邻苯二甲酸二丁酯、二辛酯和二异丁酯等，用作PVC等的增塑剂；还可用于生产不饱和聚酯树脂、醇酸树脂、染料及颜料、多种油漆、食品添加剂、医药中的缓泻剂酚酞、农药中的亚胺硫磷、灭草松以及糖精钠等。
• Sigma Aldrich:85-44-9(sigmaaldrich)
• 灭火剂:雾状水、二氧化碳、砂土。
• 防护措施:与苯甲酸同样对皮肤，粘膜有局部刺激性，有时会引起严重的炎症和发疱，并且有不少形成难以治愈的溃疡，其毒性略比苯甲酸小，对大鼠经口LD50为8.0g/kg。空气中最高容许浓度2ppm。 生产中可采用水喷淋捕集法减少车间空气中邻苯二甲酸酐的浓度，操作人员应配戴好劳保用
• {Chemica
• 蒸气压:<;0.01 mm Hg ( 20 °C)