Cytochalasin A from Drechslera dematioidea 细胞松弛素 A 来源于Drechslera dematioidea

CAS 14110-64-6 MFCD00005935

化学结构图

14110-64-6
SMILES: C[C@H]1[C@H]2[C@H](CC3C=CC=CC=3)NC(=O)[C@@]32OC(=O)C=CC(=O)CCC[C@@H](C)CC=C[C@H]3[C@H](O)C1=C |c:6,8,t:10,20,30|

化学属性

Mol. FormulaC29H35NO5
Mol. Weight477.59
Melting Point190-191 °C
TSCANo

别名和识别编码

Chemical NameCytochalasin A from Drechslera dematioidea
MDL NumberMFCD00005935
PubChem Substance ID24892882
Beilstein Registry Number949521
EC Number237-964-9
CAS Number14110-64-6
Merck Number14,2790
Synonym 细胞松弛素 A 来源于Drechslera dematioidea
Chemical Name Translation细胞松弛素 A 来源于Drechslera dematioidea
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分类

  • {SNA} Actin Inhibitors and Probes, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix, Mold, Toxins and Venoms
  • {SNA} Actin Inhibitors and Probes, Bioactive Small Molecule Alphabetical Index, CI-CZ, Cytoskeleton and Extracellular Matrix, M

相关文献及参考

  • [2]. Antonio Bottalico, et al. Cytochalasins: Structure-activity relationships. Phytochemistry Volume 29, Issue 1, 1990.
  • [1]. Kerman K, et al. An electrochemical approach for the detection of HIV-1 protease. Chem Commun (Camb). 2007 Oct 7;(37):3829-31.
  • [1]. Kerman K, et al. An electrochemical approach for the detection of HIV-1 protease. Chem Commun (Camb). 2007 Oct 7;(37):3829-31.
  • [2]. Antonio Bottalico, et al. Cytochalasins: Structure-activity relationships. Phytochemistry Volume 29, Issue 1, 1990.

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H330 Fatal if inhaled 吸入致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H300 Fatal if swallowed 吞食致命
Signal word Danger
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S20 When using do not eat or drink 使用时，不得进食，饮水；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S4 Keep away from living quarters 远离生活区；
  • S9 Keep container in a well-ventilated place 保持容器在通风良好的场所；
  • S27/28
Packing GroupII
UN Number UN1544
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒
Storage condition Light Sensitive
Hazard Codes T+

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. CI-CY - Bioactive Small Molecules
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytoskeleton and Extracellular Matrix - Cell Signaling and Neuroscience
  5. Actin Inhibitors and Probes - Cytoskeleton and Extracellular Matrix
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Type - Enzyme Inhibitors
  6. Other - Enzyme Inhibitors by Type
  1. Medical Research Areas
  2. Metabolism
  3. HIV Protease  (HIV蛋白酶)

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