2,5-二氯苯胺 2,5-二氯苯胺

CAS 95-82-9 MFCD00007667

化学结构图

95-82-9
SMILES: Nc1cc(Cl)ccc1Cl

化学属性

Mol. FormulaC6H5Cl2N
Mol. Weight162.01
Boiling Point251 °C(lit.)
Melting Point49.0 to 52.0 deg-C
Density1.401
Flash Point>110°C
TSCAYes
Autoignition Point>;374 °F
SolubilityCA. 0.56 G/L (20 ºC)
Stability对光敏感

别名和识别编码

Chemical Name2,5-二氯苯胺
CAS Number95-82-9
PubChem Substance ID87567015
EC Number202-455-2
Beilstein Registry Number12,625
MDL NumberMFCD00007667
Reaxys-RN1447438
Synonym 2,5-Dichloroaniline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Chemical Name Translation2,5-二氯苯胺
Wiswesser Line NotationZR BG EG
LabNetwork Molecule IDLN00224997
InChIInChI=1S/C6H5Cl2N/c7-4-1-2-5(8)6(9)3-4/h1-3H,9H2
Canonical SMILESNC1=CC(Cl)=CC=C1Cl
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分类

  • {SNA} Additio
  • Alpha sort, Alphabetic, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class, Chromatography, D, DIA - DIC, Environmental Standards, Pesticides & Metabolites
  • {uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; 1fragment
  • {SNA} Amines, Building Blocks, C6, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks
  • {SNA} Alphabetical Index of Analytical Standards, Amines, Analytical Standards, Analytical/Chromatography, Aromatics, Chemical Class, Chromatography,
  • {Chemicalbook} 农药中间体: 除草剂中间体: 其他类除草剂

产品应用

  • 染料中间体。

相关文献及参考

  • Beilstein:12,625
  • Short: III/31a
  • Short: III/20b
  • Nucleophilic displacement of the chloro-substituents has been carried out by heating with thiophenol in the presence of K2CO3 in NMP: J. Org. Chem., 56, 862 (1991).

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H301+H311+H331
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
Hazard Codes T,N T;N
RTECSBX2610000
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P301+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P302+P350
  • P403+P233
  • P305+P351+P338+P310
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P304+P340+P311
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P308+P311
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P305+P351+P338
  • P301+P310+P330
  • P302+P352+P312+P361+P364
  • P405 Store locked up. 上锁保管。
Signal word Danger {} {} {} {} {} {TCI}
UN Number UN3442 UN 3442 6.1/PG 2 3442
Safety Statements
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R33 Danger of cumulative effects 有累积作用的危险
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
  • R50/53
Packing GroupII
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
Hazard Class6.1
Warnings 危化品目录(2015) 
TYPE OF TEST            : LD50 - Lethal

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: OTS 206512

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 3750 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 33(4),8,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3750 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or e

Restrict 危险品

其他信息

  • 方法二:1.铁粉还原法以2,5-二氯硝基苯为原料，在稀酸介质中用铁粉还原后，经中和、分离、精制而得成品。2.加氢还原法以2,5-二氯硝基苯为原料，乙醇为介质和催化剂，在加温加压下进行加氢反应，反应产物经分离、精制而得成品。
  • 用途二:用作棉织物染色和印花的显色剂，也用作有机颜料的中间体
  • 用途三:2，5-二氯苯胺是除草剂麦草畏的中间体，也是染料和氮肥增效剂的中间体。
  • TCI Shanghai:2,5-二氯苯胺 2,5-Dichloroaniline,>;98.0%(GC)(95-82-9)
  • 毒性分级:中毒
  • Hazard Note:Toxic
  • 储运特性:库房通风低温干燥; 与氧化剂、食品添加剂、酸类分开存放
  • 常规方法:用铁桶包装，每桶净重150或200kg。贮存于通风良好、干燥、防晒的仓库内。按一般化学品规定贮运。
  • {Ch
  • 类别:有毒物品
  • MOL 文件:95-82-9.mol
  • 用途四:该品为冰染染料大红色基GG；为印染大红色布显色剂；用于合成2,5-二氯苯胺-4-磺酸等染料中间体；也可用于制造氮肥增效剂N-2,5-二氯苯基琥珀酰胺酸。
  • 色指数:37010
  • 用途五:染料中间体。
  • 急性毒性:口服-大鼠 LD50: 1600 毫克/公斤;口服-小鼠 LD50: 1600 毫克/公斤
  • MSDS 信息:2,5-二氯苯胺(95-82-9).msds
  • 防护措施:有毒。受热分解放出苯胺等有毒气体。大鼠经口LD50为2900mg/kg。生产操作人员应穿戴防护用具。生产车间应通风良好。设备应密闭。
  • 海关编码:29214210
  • Sigma Aldrich:95-82-9(sigmaaldrich)
  • Alfa Aesar:2,5-二氯苯胺,99% 2,5-Dichloroaniline, 99%(95-82-9)
  • 溶于乙醚、乙醇、苯、稀盐酸和二硫化碳，微溶于水。
  • 下游产品:2,3,4-三氟硝基苯 --> 2,5-二氯苯酚 --> 双氯芬酸钠 --> 分散黄H-4GL --> 颜料红 144 --> CI 12480 --> 2,5-二-氯-1,4-苯二胺
  • 检测方法:HPLC
  • 用途一:用作染料和颜料中间体，也用于有机合成和制取氮肥增效剂
  • 图谱信息:2,5-二氯苯胺(95-82-9)核磁图( 13 CNMR) 2,5-二氯苯胺(95-82-9)Raman光谱 2,5-二氯苯胺(95-82-9)质谱(MS) 2,5-二氯苯胺(95-82-9)红外图谱(IR1) 2,5-二氯苯胺(95-82-9)红外图谱(IR2)
  • 方法一:其制备方法是在高压釜中加入2，5-二氯硝基苯、乙醇和铂系催化剂，在85～90℃导入氢气至3～4MPa，然后停止通氢气并保温，待压力下降稳定后即达终点，将物料倾出，脱溶结晶得产品。
  • F:8
  • 上游原料:铁粉 --> 甲酸 --> 苯乙醇 --> 2,5-二氯硝基苯
  • Acros Organics:2,5-二氯苯胺 2,5-Dichloroaniline, 99%(95-82-9)
  • 可燃性危险特性:明火可燃;受热分解有毒氯化物和氮氧化物烟雾
  • 2,5-二氯苯胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 D0322 2,5-二氯苯胺 2,5-Dichloroaniline 500G 1110元 2014/06/02 D0322 2,5-二氯苯胺 2,5-Dichloroaniline 25G 150元 2010/06/21 146610010 2,5-二氯苯胺 2,5-Dichloroaniline 99% 1 KG 1806元
  • 灭火剂:泡沫、二氧化碳、干粉、砂土。

系列性分类

  1. C6 - Amines
  1. C10 - Amines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Chemicals by Class 化学分类法
  4. Amines - Chemical Class
  5. Aromatics - Amines
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Nitrogen Compounds 氮化合物
  5. Amines 胺
  6. C11 to C38

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