Tetramethylammonium hydroxide solution 四甲基氢氧化铵溶液

CAS 75-59-2 MFCD00008280

化学结构图

75-59-2
SMILES: C[N+](C)(C)C.[OH-]

化学属性

Mol. FormulaC4 H12 N . H O
Mol. Weight91.15
Density1.016
Refractive indexn20/D 1.3806
TSCAYes
Boiling Point110
Flash Point26.67°C
Melting Point62-71 ºC
Solubility可溶
Vapor Pressure17.5 mmHg ( 20 °C)
Appearance 无色结晶(常含三、五等结晶水),熔点68-71℃,极易吸潮,在空气中能迅速吸收二氧化碳,130℃时分解为甲醇和三甲胺,通常使用有10%;25%水(或醇)溶液和含结晶水化合物。
Stability对空气敏感
pH:A

别名和识别编码

Chemical NameTetramethylammonium hydroxide solution
Synonym Tetramethylammonium Hydroxide (25% w/w solution in Water) {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
MDL NumberMFCD00008280
CAS Number75-59-2
PubChem Substance ID87577222
Beilstein Registry Number3558708
EC Number200-882-9
Merck Number9224
Reaxys-RN3558708
Chemical Name Translation四甲基氢氧化铵溶液
Wiswesser Line Notation1K1&1&1 &Q
LabNetwork Molecule IDLN00193980
InChIInChI=1S/C4H12N.H2O/c1-5(2,3)4;/h1-4H3;1H2/q+1;/p-1
Canonical SMILESC[N+](C)(C)C.[OH-]
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分类

  • {SNA} Acids & Bases, Analytical Reagents, Analytical/Chro
  • {SNA} Analytical Reagents, Analytical/Chromatography, Atomic Absorption Spectroscopy (AAS), Digestion Reagents, High Purity Bases for Trace Analysis (TRACESELECT), Pure Reagents for Wet Digestion (TraceSELECT), Reagents for Inorganic Trace Analysis, Spectroscopy, Trace Analysis Reagents & Solvents
  • {SNA} β-Glucuronidase Drug Analysis Bundle, Acids & Bases, Analytical and Industrial Enzymes, Bases, Chemical Synthesis, Organic Bases, Synthetic Reagents, TMAH - Tetramethylphenylammonium hydroxide, 生化试剂, 酶、抑制剂和底物
  • {SNA} Acids & Bases,
  • {SNA}
  • {SNA} Analytical Reagents, Analytical/Chromatography, Base Soluti

产品应用

  • 在电子行业中,广泛用作硅晶片蚀刻剂、清洗剂、正胶显影剂等

相关文献及参考

  • Merck: 14,9224
  • Merck: 14,9224 Beilstein: 4,IV,145

安全信息

GHS Symbol
WGK Germany3
Hazard statements
  • H301+H311
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H301 Toxic if swallowed 吞食有毒
  • H332 Harmful if inhaled 吸入有害
  • H315 Causes skin irritation 会刺激皮肤
  • H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H370 Causes damage to organs 导致器官损伤
  • H300 Fatal if swallowed 吞食致命
  • H312 Harmful in contact with skin 皮肤接触有害
  • H302+H312
  • H300+H310
  • H331 Toxic if inhaled 吸入中毒
  • H226 Flammable liquid and vapour 易燃液体和蒸气
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes 8 F,T T T+
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P310+P330
  • P301+P330+P331+P310
  • P302+P350
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P308+P311
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Packing GroupII
UN Number 1835 2924 UN1835 UN2924
Risk Statements
  • R10 Flammable 易燃
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R21 Harmful in contact with skin 与皮肤接触有害
  • R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
  • R23 Toxic by inhalation 吸入有毒
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R24 Toxic in contact with skin 与皮肤接触有毒
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
  • R25 Toxic if swallowed 吞咽有毒
  • R27/28 Very toxic in contact with skin and if swallowed 皮肤接触及吞食都有剧毒
  • R34 Causes burns 会导致灼伤
  • R35 Causes severe burns 会导致严重灼伤
  • R36 Irritating to eyes 刺激眼睛
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性:吸入,皮肤接触和吞食都会产生十分严重的不可逆危险
  • R44 Risk of explosion if heated under confinement 密封下加热有爆炸危险
  • R48/21
  • R48/24
  • R51/53
  • R52 Harmful to aquatic organisms 对水生生物有害
  • R52/53
Safety Statements
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S33 Take precautionary measures against static discharges 对静电采取预防措施;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S4 Keep away from living quarters 远离生活区;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S57 Use appropriate containment to avoid environmental contamination 使用适当容器避免环境污染;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S7/9 Keep container tightly closed and in a well-ventilated place 保持容器严格密闭,置于通风良好的场所;
Storage condition +20°C 2-8°C 20℃ Air Sensitive {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
RTECSPA0875000
Hazard Class8
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0570994

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,688,1948

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 28,367,1926

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,688,1948

TYPE OF

其他信息

  • 图谱信息:四甲基氢氧化铵(75-59-2)红外图谱(IR1)
  • 爆炸物危险特性:对皮肤,角膜有腐蚀性
  • TCI Shanghai:四甲基氢氧化铵(约25%的水溶液) Tetramethylammonium Hydroxide (ca. 25% in Water)(75-59-2)
  • MSDS 信息:Tetramethylammonium hydroxide(75-59-2).msds
  • 可燃性危险特性:蒸气有毒; 燃烧排放有毒氮氧化物和氨气烟雾
  • 用途一:用作极谱分析试剂
  • 下游产品:聚二甲基硅氧烷 --> 107室温硫化硅橡胶 --> 聚二甲基硅氧烷
  • 急性毒性:皮下- 小鼠 LDL0: 19 毫克/ 公斤
  • 毒性分级:剧毒
  • 用途二:用作计算机硅片面的光亮剂、触刻剂等
  • F:4.4-10-34
  • MOL 文件:75-59-2.mol
  • 灭火剂:雾状水、泡沫、砂土
  • 类别:腐蚀物品
  • 制备工艺:四甲基氢氧化铵的制备方法很多,一般采用氧化银法,通过四甲基氯化铵与氧化银反应生成。但该法制备四甲基氢氧化铵的工艺复杂,原料氧化银价格昂贵,而且所得产品含较高的杂质离子,如卤素离子、碱金属离子等,用于有机硅单体催化聚合时,严重影响有机硅产品特性,更无法满足电子领域清洗和腐蚀的要求。 国外从七十年代开始采用电解法制备四甲基氢氧化铵的新工艺,并逐步取代氧化银法。用电解法制得的产品质量较好,成本低,不仅能满足有机硅生产的需要,而且进入了电子工业领域。
  • Alfa Aesar:四甲基氢氧化铵,25%w/winmethanol Tetramethylammonium hydroxide, 25% w/w in methanol(75-59-2)
  • 用途三:在电子行业中,广泛用作硅晶片蚀刻剂、清洗剂、正胶显影剂等
  • 储运特性:库房通风低温干燥; 与酸类分开存放。
  • Acros Organics:四甲基氢氧化铵 Tetramethylammonium hydroxide, 10% in water(75-59-2)
  • 敏感性:Air Sensitive
  • Sigma Aldrich:75-59-2(sigmaaldrich)
  • 产品描述:四甲基氢氧化铵(Tetramethyl ammonium hydroxide,TMAH)又称为氢氧化四甲铵、四甲基氢氧化胺,无色至淡黄色液体,是最强的有机碱,极易吸潮,有一定的氨气味,在空气中能迅速吸收二氧化碳,在室温下其蒸汽压较低,在135~145℃完全分解气化,高纯品在140℃低温处理也无微量残渣。四甲基氢氧化铵溶液无色透明有微氨臭,1(wt)%溶液PH值为12.9,是与苛性碱同等强度的强碱。将四甲基氢氧化铵水溶液在减压下浓缩可得到5个结晶水的吸湿性针状结晶,再继续浓缩脱水变成3个结晶水的结晶,再变成1个结晶水的四甲基氢氧化铵,在135~140°C分解为三甲胺和二甲基醚,通常制10%、25%的水溶液。
  • 四甲基氢氧化铵价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 80125019 四甲基氢氧化铵25% kg 840元 2011/08/23 80125015 四甲基氢氧化铵25% 50g 49.8元 2011/08/23 TT146002 四甲基氢氧化铵 25ml 190元
  • 蒸气压:17.5 mm Hg ( 20 °C)

系列性分类