4-Chloro-1,2-Diaminobenzene 4-氯-1,2-苯二胺

CAS 95-83-0 MFCD00011691

化学结构图

95-83-0
SMILES: Nc1ccc(Cl)cc1N

化学属性

Mol. FormulaC6H7ClN2
Mol. Weight142.59
Melting Point70-73°C
TSCAYes
Solubility16 G/L (20 ºC)
Boiling Point232.49 °C at 760 mmHg

别名和识别编码

Chemical Name4-Chloro-1,2-Diaminobenzene
CAS Number95-83-0
Alfabeta NameCHLORODIAMINOBENZENE 412---,
MDL NumberMFCD00011691
Synonym 4-Chlorobenzene-1,2-diamine {LY} 4-Chlorobenzene-1,2-diamine {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene-1,2-diamine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 4-Chlorobenzene
PubChem Substance ID7263
EC Number202-456-8
Beilstein Registry Number508472
Reaxys-RN508472
Chemical Name Translation4-氯-1,2-苯二胺
Wiswesser Line NotationZR BZ DG
LabNetwork Molecule IDLN00174243
InChIInChI=1S/C6H7ClN2/c7-4-1-2-5(8)6(9)3-4/h1-3H,8-9H2
Canonical SMILESC1=C(Cl)C=CC(=C1N)N
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分类

  • {SA} Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines
  • {SNA} Amine Monomers, Materials Science, Monomers, Polymer Science, Primary Amines
  • Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks, Polyamines
  • {SNA} Amine Monomers, Monomers, Polymer Science, Primary Amines, 材料科学

产品应用

  • 发生环化及环缩合反应,形成苯并咪唑

相关文献及参考

  • Beil. 13 ,IV,68
  • Aldrich MSDS 1 , 442:A / Corp MSDS 1 (1), 837:A / FT-IR 1 (1), 1237:B / FT-IR 2 (2), 2099:A / IR-Spectra (2), 651:E / IR-Spectra (3), 740:F / NMR-Reference 2 (1), 1046:D / RegBook 1 (1), 1429:G / Sigma FT-IR 1 (2), 390:D / Structure Index 1 , 223:A:4

安全信息

Warnings IRRITANT
GHS Symbol
WGK Germany3
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H351 Suspected of causing cancer 怀疑致癌
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes Xn
RTECSSS8850000
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P302+P350
  • P304+P340
  • P305+P351+P338
  • P308+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P403+P233
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Warning
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
UN Number 2811
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18750 gm/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 1,495,1980

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 136 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-63,1978

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 273 gm/kg/78W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Vol

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 40500 gm/kg/96W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 1,495,1980

{hazard_

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 259,43,1991

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 mg/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7(Suppl

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   14,207,1989

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 274 umol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   19,98,1992

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 50 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 127,107,1984

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(

Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 储运特性:库房低温通风干燥; 与强氧化剂分开存放
  • 类别:有毒物质
  • MSDS 信息:3,4-Diaminochlorobenzene(95-83-0).msds
  • 下游产品:还原棕5R
  • Sigma Aldrich:95-83-0(sigmaaldrich)
  • Acros Organics:4-Chloro-o-phenylenediamine, 96%(95-83-0)
  • F:8
  • MOL 文件:95-83-0.mol
  • Hazard Note:Irritant
  • TCI Shanghai:4-氯-1,2-苯二胺 4-Chloro-1,2-phenylenediamine,>;96.0%(GC)(95-83-0)
  • 4-氯-1,2-苯二胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C0255 4-氯-1,2-苯二胺 4-Chloro-1,2-phenylenediamine 25G 571元 2010/06/21 331861000 4-氯-1,2-苯二胺 4-Chloro-o-phenylenediamine 97% 100 GR 1278元 2010/06/21 295080050 4-氯-1,2-苯二胺 4-Chloro-o-phenylenediamine 80%, tech. 5 GR 273元
  • 上游原料:乙醇 --> 氢氧化钠 --> 乙醚 --> 氯化亚锡 --> 2-硝基-5-氯苯胺
  • 灭火剂:水, 二氧化碳, 泡沫, 砂土
  • 图谱信息:4-氯-1,2-苯二胺(95-83-0)红外图谱(IR1) 4-氯-1,2-苯二胺(95-83-0)核磁图( 1 HNMR) 4-氯-1,2-苯二胺(95-83-0)红外图谱(IR2) 4-氯-1,2-苯二胺(95-83-0)红外图谱(IR3) 4-氯-1,2-苯二胺(95-83-0)核磁图( 13 CNMR) 4-氯-1,2-苯二胺(95-83-0)质谱(MS)
  • 4-氯-1,2-苯二胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 C0255 4-氯-1,2-苯二胺 4-Chloro-1,2-phenylenediamine 25G 618元 2010/06/21 331861000 4-氯-1,2-苯二胺 4-Chloro-o-phenylenediamine 97% 100 GR 1278元 2010/06/21 295080050 4-氯-1,2-苯二胺 4-Chloro-o-phenylenediamine 80%, tech. 5 GR 273元
  • Alfa Aesar:4-氯邻苯二胺,97% 4-Chloro-o-phenylenediamine, 97%(95-83-0)

系列性分类


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