Trimethyloxonium tetrafluoroborate 三甲基氧鎓四氟硼酸

CAS 420-37-1 MFCD00011798

化学结构图

420-37-1
SMILES: C[O+](C)C.F[B-](F)(F)F

化学属性

Mol. FormulaC3H9BF4O
Mol. Weight147.91 g/mol
Density1.422
Melting Point200°C
TSCAYes
Stability对热和湿度敏感
pH-:A
Danger-Level-
Redox-

别名和识别编码

Chemical NameTrimethyloxonium tetrafluoroborate
CAS Number420-37-1
Synonym Trimethyloxonium tetrafluoroborate {LY} Trimethyloxonium tetrafluoroborate {} {LY} Trimethyloxonium tetrafluoroborate {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} { {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Trimethyloxonium tetrafluoroborate
MDL NumberMFCD00011798
EC Number206-994-4
Beilstein Registry Number3597303
PubChem Substance ID87577267
Reaxys-RN3597303
Chemical Name Translation三甲基氧鎓四氟硼酸
InChIKeyKAAQTDVQNWMZJT-UHFFFAOYSA-J
LabNetwork Molecule IDLN00235677
Canonical SMILESC[O+](C)C.F[B-](F)(F)F
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Alkyl Transfer, C-X Bond Formation (Non-Halogen), Chemical Synthesis, Synthetic Reagents
  • Miscellaneous Reagents

产品应用

  • 米尔文盐(Meerwein salt),是一种强的亲电子甲基化试剂,用于氢氧基基团的甲基化。可用于复杂多步骤地合成海洋天然产品spirastrellolide。

相关文献及参考

  • Beilstein:1(4)1248
  • Trialkyloxonium salts, also known as Meerwein's salts, are powerful alkylating agents under mild conditions. For general reactions of trialkyloxonium salts, see Triethyl­oxonium tetrafluoroborate, A14420. For a brief feature of their uses in synthesis, see: Synlett, 195 (2004).
  • N,N-Dialkyl arylcarboxamides, useful as substrates for directed metallation reactions, can be converted to methyl esters in high yield: Tetrahedron, 56, 9875 (2000).
  • Curphey, T.J. et al.: Org. Synth. 6, 1019 (1968);
  • Alkylation of ethylene thioacetals proceeds only to the monoalkyl salt unless water is added, when the thioacetal is cleaved to give the carbonyl compound and the tetraalkyl ethane bis-sulfonium salt: Synthesis, 135 (1981). Alkylation on S to promote leaving group ability has also been used in a synthesis of oxiranes from ß-hydroxy sulfides: J. Am. Chem. Soc., 95, 3429 (1973); J. Chem. Soc., Chem. Commun., 714 (1975).

安全信息

Signal word Danger
GHS Symbol
WGK Germany3
Safety Statements
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S43 In case of fire use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add -?Never use water) 着火时使用(指明具体的消防器材种类,如果用水增加危险,注明“禁止用水”
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R14 Reacts violently with water 遇水会猛烈反应
  • R34 Causes burns 会导致灼伤
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P330+P331
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Packing GroupII
UN Number 3261
Storage condition -20°C, stored under nitrogen {LY} -20°C, stored under nitrogen <0°C <;0 Moisture Sensitive {} {LY} -20°C, stored under nitrogen {} {} {LY} -20°C, stored under nitrogen {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C, stored under nitr
Hazard Codes 8 C
Hazard Class8
Restrict -

其他信息

  • 下游产品:5-氨基-2-甲氧基-3-溴吡啶
  • Sigma Aldrich:420-37-1(sigmaaldrich)
  • TCI Shanghai:三甲基氧四氟硼酸盐 Trimethyloxonium Tetrafluoroborate,>;95.0%(T)(420-37-1)
  • Hazard Note:Corrosive/Freeze
  • Acros Organics:三甲基氧鎓四氟硼酸 Trimethyloxonium tetrafluoroborate, 95%(420-37-1)
  • MOL 文件:420-37-1.mol
  • Alfa Aesar:三甲基四氟硼酸,97+% Trimethyloxonium tetrafluoroborate, 96%(420-37-1)
  • 存储注意事项:惰性气体保护;湿度敏感
  • F:3-10-21
  • 敏感性:Moisture Sensitive
  • 三甲基氧鎓四氟硼酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T1507 三甲基氧四氟硼酸盐 Trimethyloxonium Tetrafluoroborate 5G 385元 2014/06/02 T1507 三甲基氧四氟硼酸盐 Trimethyloxonium Tetrafluoroborate 25G 1260元 2010/06/21 421960100 三甲基氧鎓四氟硼酸 Trimethyloxonium tetrafluoroborate 95% 10 GR 612元

系列性分类


相关产品推荐